CAS 142825-10-3|L-Sulforaphane
| Common Name | L-Sulforaphane | ||
|---|---|---|---|
| CAS Number | 142825-10-3 | Molecular Weight | 177.288 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 368.2±25.0 °C at 760 mmHg |
| Molecular Formula | C6H11NOS2 | Melting Point | / |
| MSDS | USA | Flash Point | 176.5±23.2 °C |
Names
| Name | (R)-sulforaphane |
|---|---|
| Synonym | More Synonyms |
L-Sulforaphane BiologicalActivity
| Description | (R)-Sulforaphane is a highly potent inducer of the Keap1/Nrf2/ARE pathway. (R)-Sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer[1][2]. |
|---|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
| References | [1]. De Nicola GR, et al. Novel gram-scale production of enantiopure R-sulforaphane from Tuscan black kale seeds. Molecules. 2014 May 27;19(6):6975-86. [2]. Abdull Razis AF, et al. The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer. Int J Cancer. 2011 Jun 15;128(12):2775-82. |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 368.2±25.0 °C at 760 mmHg |
| Molecular Formula | C6H11NOS2 |
| Molecular Weight | 177.288 |
| Flash Point | 176.5±23.2 °C |
| Exact Mass | 177.028198 |
| PSA | 80.73000 |
| LogP | 0.23 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.567 |
| InChIKey | SUVMJBTUFCVSAD-SNVBAGLBSA-N |
| SMILES | CS(=O)CCCCN=C=S |
| Storage condition | -20°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves |
|---|---|
| Hazard Codes | Xi |
| Safety Phrases | S22-S23-S24/25 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2930909090 |
Customs
| HS Code | 2930909090 |
|---|---|
| Summary | 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Articles18
More Articles| Sulforaphane prevents doxorubicin-induced oxidative stress and cell death in rat H9c2 cells. Int. J. Mol. Med. 36 , 53-64, (2015) Sulforaphane, a natural isothiocyanate compound found in cruciferous vegetables, has been shown to exert cardioprotective effects during ischemic heart injury. However, the effects of sulforaphane on ... | |
| In vitro metabolic conversion of the organic breakdown products of glucosinolate to goitrogenic thiocyanate anion. J. Sci. Food Agric. 95 , 2244-51, (2015) Glucosinolates are abundant in Brassicaceae vegetables, and they are degraded into various organic breakdown products (BPs) (R-CN, -NCS and -SCN) by myrosinase when plant tissues are damaged. This stu... | |
| Nrf2 Activation Promotes Keratinocyte Survival during Early Skin Carcinogenesis via Metabolic Alterations. Cancer Res. 75 , 4817-29, (2015) Pharmacologic activation of the transcription factor NRF2 has been suggested to offer a strategy for cancer prevention. In this study, we present evidence from murine tumorigenesis experiments suggest... |
Synonyms
| UNII:41684WL1GL |
| 1-Isothiocyanato-4-(methylsulfinyl)butane |
| SULFORAPHANE, (±)- |
| 4-Isothiocyanatobutyl methyl sulfoxide |
| 4-Methylsulfinylbutyl isothiocyanate |
| 1-Isothiocyanato-4-[(R)-methylsulfinyl]butane |
| 4-(Methylsulfinyl)butyl isothiocyanate |
| Butane, 1-isothiocyanato-4-[(R)-(1R)-methylsulfinyl]- |
| Butane, 1-isothiocyanato-4-(methylsulfinyl)- |
| (R)-sulforaphane |
| MFCD09039283 |
| DL-Sulforaphane |
| (R)-1-isothiocyanato-4-(methylsulfinyl)butane |
| Sulforaphane |
| (-)-Sulforaphane |
| L-Sulforaphane |
| 4-isothiocyanatobutyl methyl (R)-sulfoxide |
| (R)-1-Isothiocyanato-4-(methylsulfinyl)butane,4-Methylsulfinylbutyl isothiocyanate |
| SCN4SO&1 |
