CAS 14341-87-8|N-Acetyl-D-(2,3,3,4,4-2H5)glutamic acid

Introduction:Basic information about CAS 14341-87-8|N-Acetyl-D-(2,3,3,4,4-2H5)glutamic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameN-Acetyl-D-(2,3,3,4,4-2H5)glutamic acid
CAS Number14341-87-8Molecular Weight194.20
Density1.4±0.1 g/cm3Boiling Point495.9±35.0 °C at 760 mmHg
Molecular FormulaC7H6D5NO5Melting Point/
MSDS/Flash Point253.7±25.9 °C

Names

Namen-acetyl-d-glutamic-2,3,3,4,4-d5 acid
SynonymMore Synonyms

N-Acetyl-D-(2,3,3,4,4-2H5)glutamic acid BiologicalActivity

DescriptionAc-D-Glu-OH-d5 is the deuterium labeled Ac-D-Glu-OH.
In VitroStable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point495.9±35.0 °C at 760 mmHg
Molecular FormulaC7H6D5NO5
Molecular Weight194.20
Flash Point253.7±25.9 °C
Exact Mass194.095108
PSA103.70000
LogP-2.24
Vapour Pressure0.0±2.7 mmHg at 25°C
Index of Refraction1.502

Synonyms

D-Glutamic-2,3,3,4,4-d acid, N-acetyl-
N-Acetyl-D-(2,3,3,4,4-H)glutamic acid
CAS 14341-86-7|Succinic anhydride-2,2,3,3-d4
CAS 14341-88-9|D-Glutamic acid-d5
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