CAS 1435-55-8|Hydroquinidine
Introduction：Basic information about CAS 1435-55-8|Hydroquinidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Hydroquinidine | ||
|---|---|---|---|
| CAS Number | 1435-55-8 | Molecular Weight | 326.433 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 498.4±30.0 °C at 760 mmHg |
| Molecular Formula | C20H26N2O2 | Melting Point | 169-170 ºC |
| MSDS | ChineseUSA | Flash Point | 255.2±24.6 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | Hydroquinidine |
|---|---|
| Synonym | More Synonyms |
Hydroquinidine BiologicalActivity
| Description | Hydroquinidine is an antiarrhythmic agent. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 498.4±30.0 °C at 760 mmHg |
| Melting Point | 169-170 ºC |
| Molecular Formula | C20H26N2O2 |
| Molecular Weight | 326.433 |
| Flash Point | 255.2±24.6 °C |
| Exact Mass | 326.199432 |
| PSA | 45.59000 |
| LogP | 3.77 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.626 |
| InChIKey | LJOQGZACKSYWCH-LHHVKLHASA-N |
| SMILES | CCC1CN2CCC1CC2C(O)c1ccnc2ccc(OC)cc12 |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 12 mg/kg
- TOXIC EFFECTS :
- Behavioral - hallucinations, distorted perceptions Behavioral - headache Cardiac - EKG changes not diagnostic of specified effects
- REFERENCE :
- CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW. Volume(issue)/page/year: 18,659,1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 56500 ug/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 84,184,1945
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 + H312 + H332 |
| Precautionary Statements | P280 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn |
| Risk Phrases | 20/21/22 |
| Safety Phrases | 36/37-36 |
| RIDADR | UN 1544 |
| WGK Germany | 3 |
| RTECS | MX3016000 |
| Packaging Group | III |
| HS Code | 2933990090 |
Customs
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| EINECS 215-862-5 |
| HYDROQUINIDINE |
| (9S)-6'-Methoxy-10,11-dihydrocinchonan-9-ol |
| MFCD00135599 |
| (+)-Dihydroquinidine |
| (9S)-10,11-Dihydro-6'-methoxycinchonan-9-ol |
| Cinchonan-9-ol, 10,11-dihydro-6'-methoxy-, (9S)- |
| dihydroquinidine |
| hydroconchinine |
