CAS 143-98-6|Dextrorphan tartrate

Introduction：Basic information about CAS 143-98-6|Dextrorphan tartrate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Articles1
6. Synonyms

Common Name	Dextrorphan tartrate
CAS Number	143-98-6	Molecular Weight	407.457
Density	/	Boiling Point	410.4ºC at 760 mmHg
Molecular Formula	C₂₁H₂₉NO₇	Melting Point	201-204°C
MSDS	ChineseUSA	Flash Point	207.2ºC
Symbol	GHS02, GHS06, GHS08	Signal Word	Danger

Names

Name	Dextrorphan tartrate
Synonym	More Synonyms

Chemical & Physical Properties

Boiling Point	410.4ºC at 760 mmHg
Melting Point	201-204°C
Molecular Formula	C₂₁H₂₉NO₇
Molecular Weight	407.457
Flash Point	207.2ºC
Exact Mass	407.194397
PSA	138.53000
LogP	0.89570
Appearance of Characters	white
Vapour Pressure	2.55E-07mmHg at 25°C
InChIKey	RWTWIZDKEIWLKQ-XCPWPWHNSA-N
SMILES	CN1CCC23CCCCC2C1Cc1ccc(O)cc13.O=C(O)C(O)C(O)C(=O)O
Storage condition	−70°C
Water Solubility	H2O: >10mg/mL

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QD1930000

CAS REGISTRY NUMBER :: 143-98-6

LAST UPDATED :: 199106

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C17-H23-N-O.C4-H6-O6

MOLECULAR WEIGHT :: 407.51

WISWESSER LINE NOTATION :: T6 G666/FQ 2AF Q FX ONT&TTJ IQ O &622 QVYQYVQ -D &621

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 109,189,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 109,189,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 385 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 109,189,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 109,189,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 42 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 31ZPAG "Synthetic Analgesics," Oxford, Pergamon Press, 1966 Volume(issue)/page/year: 2,77,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 17414 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 145,11,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 27500 ug/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Behavioral - rigidity (including catalepsy) Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 109,189,1953

Safety Information

Symbol	GHS02, GHS06, GHS08
Signal Word	Danger
Hazard Statements	H225-H301 + H311 + H331-H370
Precautionary Statements	P210-P260-P280-P301 + P310-P311
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn
Risk Phrases	R22
Safety Phrases	7-16-36/37-45
RIDADR	UN1230 - class 3 - PG 2 - Methanol, solution
RTECS	QD1930000

Articles1

The role of excitatory amino acids and NMDA receptors in traumatic brain injury.

Science 244 , 798, (1989)

Brain injury induced by fluid percussion in rats caused a marked elevation in extracellular glutamate and aspartate adjacent to the trauma site. This increase in excitatory amino acids was related to ...

Synonyms

(2R,3R)-2,3-Dihydroxysuccinic acid - (9α,13α,14α)-17-methylmorphinan-3-ol (1:1)

Levorphanol tartrate

1,3,4,9,10,10a-Hexahydro-11-methyl-2H-10,4a-iminoethanophenanthren-6-ol tartrate,d

d-1,3,4,9,10,10a-Hexahydro-11-methyl-2H-10,4a-iminoethanophenanthren-6-ol Tartrate

Dextrorphan Tartrate Salt

17-Methyl-morphinan-3-ol,Lg-Hydrogentartrat

d-3-Hydroxy-N-methylmorphinan tartrate

Butanedioic acid, 2,3-dihydroxy-, (2R,3R)-, compd. with (9α,13α,14α)-17-methylmorphinan-3-ol (1:1)

17-methyl-morphinan-3-ol,Lg-hydrogentartrate

MFCD00151495

(+)-(9a,13a,14a)-17-methylmorphinan-3-ol Tartrate (1:1) (Salt)

Dextrophan tartrate

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