CAS 144822-63-9|5'-O-DMT-2'-ara-F-2'-dU

Introduction:Basic information about CAS 144822-63-9|5'-O-DMT-2'-ara-F-2'-dU, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name5'-O-DMT-2'-ara-F-2'-dU
CAS Number144822-63-9Molecular Weight534.53
Density1.38Boiling Point/
Molecular FormulaC29H27FN2O7Melting Point/
MSDS/Flash Point/

Names

Name1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-2,4(1H,3H)-pyrimidinedione
SynonymMore Synonyms

5'-O-DMT-2'-ara-F-2'-dU BiologicalActivity

Description5’-O-DMT-2’-deoxy-2’-fluoro-β-D-arabinouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog
References

[1]. Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25.  

Chemical & Physical Properties

Density1.38
Molecular FormulaC29H27FN2O7
Molecular Weight534.53
Exact Mass548.19600
PSA112.01000
LogP3.15890
Index of Refraction1.647
InChIKeyCSSFZSSZXOCCJB-KCPYNUOSSA-N
SMILESCOc1ccc(C(OCC2OC(n3ccc(=O)[nH]c3=O)C(F)C2O)(c2ccccc2)c2ccc(OC)cc2)cc1
Storage condition2-8℃

Synonyms

5'-O-DMT-2'-ara-F-2'-dU
CAS 14481-08-4|bis(2,2,6,6-tetramethyl-3,5-heptanedionato)nickel(ii)
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