CAS 83148-91-8|sophoridine

Introduction:Basic information about CAS 83148-91-8|sophoridine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Namesophoridine
CAS Number83148-91-8Molecular Weight248.36
Density1.164 g/cm3Boiling Point396.738ºC at 760 mmHg
Molecular FormulaC15H24N2OMelting Point/
MSDS/Flash Point172.748ºC

Names

NameSophoridine
SynonymMore Synonyms

sophoridine BiologicalActivity

Descriptiond-Sophoridine ((+)-Sophoridine) is the dextro isoform of Sophoridine (HY-N1373), which is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity[1].
Related CatalogSignaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cancer
References

[1]. Xu Z, et al. Sophoridine induces apoptosis and S phase arrest via ROS-dependent JNK and ERK activation in human pancreatic cancer cells. J Exp Clin Cancer Res. 2017 Sep 11;36(1):124.  

Chemical & Physical Properties

Density1.164 g/cm3
Boiling Point396.738ºC at 760 mmHg
Molecular FormulaC15H24N2O
Molecular Weight248.36
Flash Point172.748ºC
Exact Mass248.18900
PSA23.55000
LogP1.74750
InChIKeyZSBXGIUJOOQZMP-UHFFFAOYSA-N
SMILESO=C1CCCC2C3CCCN4CCCC(CN12)C34

Synonyms

matridin-15-one
(2R,3R)-2,3-bis(4-hydroxy-3-methoxybenzyl)-4-butanolide
S-GINSENOSIDE RG3
(2R,3R)-2,3-bis(4-hydroxy-3-methoxybenzyl)butyrolactone
(3R,4R)-rel-Dihydro-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone
(E)-3,4-di[(4-hydroxy-3-methoxyphenyl)methyl]dihydro-2(3H)-furanone
SOPHORIDINE (REFERENCE GRADE)
MATRIDIN-15-ONE, (6B,7B,11A)-
rac Matairesinol
(8R,8'R)-(-)-matairesinol
Allomatrine
trans-Dihydro-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone
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