Introduction:Basic information about CAS 83148-91-8|sophoridine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | sophoridine |
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| CAS Number | 83148-91-8 | Molecular Weight | 248.36 |
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| Density | 1.164 g/cm3 | Boiling Point | 396.738ºC at 760 mmHg |
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| Molecular Formula | C15H24N2O | Melting Point | / |
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| MSDS | / | Flash Point | 172.748ºC |
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Names
| Name | Sophoridine |
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| Synonym | More Synonyms |
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sophoridine BiologicalActivity
| Description | d-Sophoridine ((+)-Sophoridine) is the dextro isoform of Sophoridine (HY-N1373), which is a quinolizidine alkaloid isolated from Leguminous plant Sophora flavescens. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor agent candidate for pancreatic cancer with well-tolerated toxicity[1]. |
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| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cancer |
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| References | [1]. Xu Z, et al. Sophoridine induces apoptosis and S phase arrest via ROS-dependent JNK and ERK activation in human pancreatic cancer cells. J Exp Clin Cancer Res. 2017 Sep 11;36(1):124. |
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Chemical & Physical Properties
| Density | 1.164 g/cm3 |
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| Boiling Point | 396.738ºC at 760 mmHg |
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| Molecular Formula | C15H24N2O |
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| Molecular Weight | 248.36 |
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| Flash Point | 172.748ºC |
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| Exact Mass | 248.18900 |
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| PSA | 23.55000 |
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| LogP | 1.74750 |
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| InChIKey | ZSBXGIUJOOQZMP-UHFFFAOYSA-N |
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| SMILES | O=C1CCCC2C3CCCN4CCCC(CN12)C34 |
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Synonyms
| matridin-15-one |
| (2R,3R)-2,3-bis(4-hydroxy-3-methoxybenzyl)-4-butanolide |
| S-GINSENOSIDE RG3 |
| (2R,3R)-2,3-bis(4-hydroxy-3-methoxybenzyl)butyrolactone |
| (3R,4R)-rel-Dihydro-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone |
| (E)-3,4-di[(4-hydroxy-3-methoxyphenyl)methyl]dihydro-2(3H)-furanone |
| SOPHORIDINE (REFERENCE GRADE) |
| MATRIDIN-15-ONE, (6B,7B,11A)- |
| rac Matairesinol |
| (8R,8'R)-(-)-matairesinol |
| Allomatrine |
| trans-Dihydro-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone |