CAS 83602-39-5|Cyclosporin H

Introduction:Basic information about CAS 83602-39-5|Cyclosporin H, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameCyclosporin H
CAS Number83602-39-5Molecular Weight1216.638
Density1.0±0.1 g/cm3Boiling Point1282.0±65.0 °C at 760 mmHg
Molecular FormulaC62H111N11O12Melting Point162-165ºC
MSDS/Flash Point729.1±34.3 °C

Names

NameCyclosporin H
SynonymMore Synonyms

Cyclosporin H BiologicalActivity

DescriptionCyclosporin H, a viral transduction enhancer, increases lentiviral transduction up to 10-fold in human cord blood-derived hematopoietic stem and progenitor cells (HSPCs). Cyclosporin H displays an additive effect when combined with Rapamycin or prostaglandin E2. Cyclosporin H lacks immunosuppressant activity of cyclosporin A.
Related CatalogSignaling Pathways >>Others >>Others

Chemical & Physical Properties

Density1.0±0.1 g/cm3
Boiling Point1282.0±65.0 °C at 760 mmHg
Melting Point162-165ºC
Molecular FormulaC62H111N11O12
Molecular Weight1216.638
Flash Point729.1±34.3 °C
Exact Mass1215.857056
PSA270.01000
LogP4.28
Vapour Pressure0.0±0.6 mmHg at 25°C
Index of Refraction1.469
InChIKeyPMATZTZNYRCHOR-JLPRAAIDSA-N
SMILESCC=CCC(C)C(O)C1C(=O)NC(CC)C(=O)N(C)CC(=O)N(C)C(CC(C)C)C(=O)NC(C(C)C)C(=O)N(C)C(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)N(C)C(CC(C)C)C(=O)N(C)C(CC(C)C)C(=O)N(C)C(C(C)C)C(=O)N1C

Synonyms

(3S,6S,9S,12R,15S,18S,21R,24S,30S)-30-Ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methyl-4-hexen-1-yl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,22,25,28-decamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
CyclosporinH
1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone, 30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methyl-4-hexen-1-yl]-1,4,7,10,12,15,19,22,25,28-decamethyl-3,21-bis(1-methylethyl)-6,9,18,24-tetrakis(2-methylpropyl)-, (3S,6S,9S,12R,15S,18S,21R,24S,30S)-
cyclosiversioside H
Cyclosporin Impurity 8
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