CAS 84878-61-5|Maduramicin ammonium

Introduction：Basic information about CAS 84878-61-5|Maduramicin ammonium, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Maduramicin ammonium BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Articles1
6. Synonyms

Common Name	Maduramicin ammonium
CAS Number	84878-61-5	Molecular Weight	934.158
Density	/	Boiling Point	913.9ºC at 760 mmHg
Molecular Formula	C₄₇H₈₃NO₁₇	Melting Point	173-176ºC
MSDS	ChineseUSA	Flash Point	255.5ºC
Symbol	GHS06	Signal Word	Danger

Names

Name	Maduramicin
Synonym	More Synonyms

Maduramicin ammonium BiologicalActivity

Description	Maduramicin ammonium (Maduramycin ammonium) is isolated from the actinomycete Actinomadura rubra. Maduramicin ammonium (Maduramycin ammonium) is an anticoccidial agent for the the treatment of Eimeria spp., E. adenoeides, E. gallopavonis, and E. dispersa infection[1]. Maduramicin ammonium (Maduramycin ammonium) induces cell apoptosis in chicken myocardial cells via intrinsic and extrinsic pathways[2].
Related Catalog	Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial
Target	IC50: bacterial; apoptosis[1]
References	[1]. McDougald LR, et al. Efficacy of maduramicin ammonium against coccidiosis in turkeys under laboratory and floor-pen conditions.Avian Dis. 1990 Jul-Sep;34(3):634-8. [2]. Gao X, et al.Maduramicin induces apoptosis in chicken myocardial cells via intrinsic and extrinsic pathways.Toxicol In Vitro. 2018 Aug;50:190-200.

Chemical & Physical Properties

Boiling Point	913.9ºC at 760 mmHg
Melting Point	173-176ºC
Molecular Formula	C₄₇H₈₃NO₁₇
Molecular Weight	934.158
Flash Point	255.5ºC
Exact Mass	933.566101
PSA	211.58000
LogP	3.35840
InChIKey	WQGJEAMPBSZCIF-VEKNOCPUSA-N
SMILES	COC1CC(OC2CC(C3OC(C)(O)C(C)CC3C)OC2C2(C)CCC(C3(C)CCC4(CC(O)C(C)C(C(C)C5OC(O)(CC(=O)[O-])C(C)C(OC)C5OC)O4)O3)O2)OC(C)C1OC.[NH4+]
Storage condition	0-6°C

Safety Information

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H300 + H310-H319
Precautionary Statements	Missing Phrase - N15.00950417-P262-P280-P302 + P352 + P310-P305 + P351 + P338-P361 + P364
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T+:Verytoxic;
Risk Phrases	R25;R27;R36
Safety Phrases	S26-S28-S36/37-S45
RIDADR	UN 2811
Packaging Group	III
Hazard Class	6.1

Articles1

Maduramicin inhibits proliferation and induces apoptosis in myoblast cells.

PLoS ONE 9(12) , e115652, (2014)

Maduramicin, a polyether ionophore antibiotic derived from the bacterium Actinomadura yumaensis, is currently used as a feed additive against coccidiosis in poultry worldwide. It has been clinically o...

Synonyms

MADUBAMYCIN AMMONIUM

[(2R,3S,4S,5R,6S)-6-{(1R)-1-[(2S,5R,7S,8R,9S)-2-{(2S,2'R,3'S,5R,5'R)-3'-{[(2R,4S,5S,6S)-4,5-Dimethoxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-5'-[(2S,3S,5R,6S)-6-hydroxy-3,5,6-trimethyltetrahydro-2H-pyran-2-yl]-2-methyloctahydro-2,2'-bifuran-5-yl}-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]ethyl}-2-hydroxy-4,5-dimethoxy-3-methyltetrahydro-2H-pyran-2-yl]acetic acid ammoniate (1:1) (non-preferred name)

Maduramicin

Maduramicin ammonium

MADURAMICINAMMONIUM

MADURAMINIC AMMONIUM

Maduramycin

Maduramycin ammonium

MADURAMICIN AMMONIUM PREMIX

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