CAS 86168-78-7|Sermorelin

Introduction:Basic information about CAS 86168-78-7|Sermorelin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameSermorelin
CAS Number86168-78-7Molecular Weight3357.882
Density1.5±0.1 g/cm3Boiling Point/
Molecular FormulaC149H246N44O42SMelting Point/
MSDSUSAFlash Point/

Names

Namesermorelin
SynonymMore Synonyms

Sermorelin BiologicalActivity

DescriptionSermorelin is a Growth Hormone Releasing Hormone (GHRH) produced by the brain that stimulates the production and release of Growth Hormone (GH).
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>OthersPeptides

Chemical & Physical Properties

Density1.5±0.1 g/cm3
Molecular FormulaC149H246N44O42S
Molecular Weight3357.882
Exact Mass3355.818604
PSA1472.20000
LogP-3.92
Index of Refraction1.650
InChIKeyWGWPRVFKDLAUQJ-TWFXBKMCSA-N
SMILESCCC(C)C(NC(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C(N)Cc1ccc(O)cc1)C(=O)NC(Cc1ccccc1)C(=O)NC(C(=O)NC(CC(N)=O)C(=O)NC(CO)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(N)=O)C(=O)NC(CC(=O)O)C(=O)NC(C(=O)NC(CCSC)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(N)=O)C(C)CC)C(C)C)C(C)O
Storage condition−20°C

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADRNONH for all modes of transport
WGK Germany3

Articles30

More Articles
Neurotransmitter-mediated action of an antagonist of growth hormone-releasing hormone on anxiolysis in mice

Behav. Brain Res. 233(1) , 232-6, (2012)

Highlights ► The involvement of transmitters in the anxiolytic action of GH-RH antagonist, MZ-4-71, has been tested in plus maze. ► In the experiments the animals were pretreated with phenoxybenzamine...

Inhibitory effects of antagonists of growth hormone-releasing hormone on growth and invasiveness of PC3 human prostate cancer.

Int. J. Cancer 132(4) , 755-65, (2013)

New approaches are needed to the therapy of advanced prostate cancer. This study determined the effect of growth hormone-releasing hormone (GHRH) antagonists, JMR-132 and JV-1-38 on growth of PC3 tumo...

Novel antagonists of growth hormone-releasing hormone inhibit growth and vascularization of human experimental ovarian cancers.

Cancer 118(3) , 670-80, (2012)

Antagonists of growth hormone-releasing hormone (GHRH) inhibit the proliferation of various human cancer cell lines and experimental tumors by mechanisms that include direct action on GHRH receptors i...

Synonyms

TYR-ALA-ASP-ALA-ILE-PHE-THR-ASN-SER-TYR-ARG-LYS-VAL-LEU-GLY-GLN-LEU-SER-ALA-ARG-LYS-LEU-LEU-GLN-ASP-ILE-MET-SER-ARG-NH2
Sermorelina
Sermorelinum
Tyrosylalanyl-α-aspartylalanylisoleucylphenylalanylthreonylasparaginylseryltyrosylarginyllysylvalylleucylglycylglutaminylleucylserylalanylarginyllysylleucylleucylglutaminyl-α-aspartylisoleucyl methionylserylargininamide
Argininamide, tyrosylalanyl-α-aspartylalanylisoleucylphenylalanylthreonylasparaginylseryltyrosylarginyllysylvalylleucylglycylglutaminylleucylserylalanylarginyllysylleucylleucylglutaminyl-α-asp artylisoleucylmethionylseryl-
Sermoreline
MFCD00076559
YaDAIFTNSYRKVLGQLSARKLLQDIMSR-NH2
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