Introduction：Basic information about CAS 217438-17-0|SB 268262, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | SB 268262 |
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| CAS Number | 217438-17-0 | Molecular Weight | 401.46 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C18H15N3O4S2 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | / |
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| Symbol |
GHS07 | Signal Word | Warning |
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Names
| Name | N-Methyl-N-(2-methylphenyl)-3-nitro-4-(1,3-thiazol-2-ylsulfinyl)b enzamide |
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| Synonym | More Synonyms |
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SB 268262 BiologicalActivity
| Description | CGRP antagonist 4 is an antagonist of calcitonin gene-related peptide (CGRP) receptor. CGRP antagonist 4 shows the highest affinity for CGRP receptors in the human brain. CGRP antagonist 4 can be used to study the binding properties of non-peptide calcitonin gene-related peptide (CGRP) receptor antagonist (gepants) in rat, pig and human menes [1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
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| References | [1]. Warfvinge K, et al. The Presence of Calcitonin Gene-Related Peptide and Its Receptors in Rat, Pig and Human Brain: Species Differences in Calcitonin Gene-Related Peptide Pharmacology. Pharmacology. 2019;104(5-6):332-341. |
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Chemical & Physical Properties
| Molecular Formula | C18H15N3O4S2 |
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| Molecular Weight | 401.46 |
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| Exact Mass | 401.05000 |
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| PSA | 143.54000 |
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| LogP | 5.19190 |
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Safety Information
| Symbol |
GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H302-H319 |
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| Precautionary Statements | P305 + P351 + P338 |
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| RIDADR | NONH for all modes of transport |
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Synonyms
| (+/-)-SB-273779 N-Methyl-N-(2-methylphenyl)-3-nitro-4-(2-thiazolylsulfinyl)-benzamide |
