Introduction：Basic information about CAS 118248-91-2|Fodipir, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Fodipir |
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| CAS Number | 118248-91-2 | Molecular Weight | 638.46 |
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| Density | 1.657g/cm3 | Boiling Point | 1049.1ºC at 760mmHg |
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| Molecular Formula | C22H32N4O14P2 | Melting Point | / |
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| MSDS | / | Flash Point | 588.3ºC |
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Names
| Name | 2,2'-{1,2-Ethanediylbis[({3-hydroxy-2-methyl-5-[(phosphonooxy)met hyl]-4-pyridinyl}methyl)imino]}diacetic acid (non-preferred name) |
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| Synonym | More Synonyms |
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Fodipir BiologicalActivity
| Description | Fodipir is an active metabolite of mangafodipir, involved in mangafodipir-mediated cytoprotection against 7β-hydroxycholesterol-induced cell death. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| In Vitro | Fodipir is an active metabolite of mangafodipir, involved in mangafodipir-mediated cytoprotection against 7β-hydroxycholesterol-induced cell death. Fodipir (Dp-dp; Dipyridoxyl diphosphate; 100 μM) shows the best cytopretective effect on 7β-OH-mediated cell death after treatment for 8 h. Fodipir also reduces 7β-OH-induced cellular ROS production and lysosomal membrane permeabilization (LMP)[1]. |
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| References | [1]. Laskar A, et al. Fodipir and its dephosphorylated derivative dipyridoxyl ethyldiamine are involved in mangafodipir-mediated cytoprotection against 7β-hydroxycholesterol-induced cell death. Pharmacology. 2013;92(3-4):182-6. |
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Chemical & Physical Properties
| Density | 1.657g/cm3 |
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| Boiling Point | 1049.1ºC at 760mmHg |
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| Molecular Formula | C22H32N4O14P2 |
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| Molecular Weight | 638.46 |
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| Flash Point | 588.3ºC |
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| PSA | 309.69000 |
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| LogP | 0.13230 |
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| Vapour Pressure | 0mmHg at 25°C |
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| Index of Refraction | 1.655 |
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| InChIKey | SQKUFYLUXROIFM-UHFFFAOYSA-N |
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| SMILES | Cc1ncc(COP(=O)(O)O)c(CN(CCN(CC(=O)O)Cc2c(COP(=O)(O)O)cnc(C)c2O)CC(=O)O)c1O |
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Synonyms
| N,N'-dipyridoxylethylenediamine-N,N'-diacetic acid-5,5'-bis(phosphate) dihydrate |
| N,N'-di-p-toluoyl-p-benzoquinone diimine |
| Benzamide,N,N'-2,5-cyclohexadiene-1,4-diylidenebis[4-methyl |
| Fodipir |
