Introduction：Basic information about CAS 199119-18-1|T 98475, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | T 98475 |
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| CAS Number | 199119-18-1 | Molecular Weight | 657.77 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C37H37F2N3O4S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Isopropyl 3-{[benzyl(methyl)amino]methyl}-7-(2,6-difluorobenzyl)- 2-[4-(isobutyrylamino)phenyl]-4-oxo-4,7-dihydrothieno[2,3-b]pyrid ine-5-carboxylate |
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T 98475 BiologicalActivity
| Description | T-98475 (Compound 26d) is a potent, orally active, non-peptide luteinizing hormone-releasing hormone (LHRH) receptor antagonist with an IC50 of 0.2 nM[1]. |
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| Related Catalog | Research Areas >>EndocrinologySignaling Pathways >>Others >>Others |
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| Target | IC50: 0.2 nM (human LHRH receptor), 2 nM (monkey LHRH receptor), 4 nM (monkey anterior pituitaries), 60 nM (rat anterior pituitaries)[1] |
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| References | [1]. Imada T, et al. Design, synthesis, and structure-activity relationships of thieno[2,3-b]pyridin-4-one derivatives as a novel class of potent, orally active, non-peptide luteinizing hormone-releasing hormone receptor antagonists. J Med Chem. 2006 Jun 29;49(13):3809-25. |
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Chemical & Physical Properties
| Molecular Formula | C37H37F2N3O4S |
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| Molecular Weight | 657.77 |
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| Exact Mass | 657.24700 |
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| PSA | 108.88000 |
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| LogP | 7.92120 |
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