CAS 53749-61-4|Substance P (2-11)

Introduction:Basic information about CAS 53749-61-4|Substance P (2-11), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameSubstance P (2-11)
CAS Number53749-61-4Molecular Weight1191.44000
Density/Boiling Point/
Molecular FormulaC57H86N14O12SMelting Point/
MSDS/Flash Point/

Names

Namesubstance p (2-11)
SynonymMore Synonyms

Substance P (2-11) BiologicalActivity

DescriptionSubstance P (2-11) is a substance P (SP) fragment peptide. Substance P (2-11) has contracting activities on guinea pig ileum. Substance P (2-11) inhibits the permeation of 3H SP in BBMEC monolayers[1][2].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease
References

[1]. Yanaihara N, et al. Immunological aspects of secretin, substance P, and VIP. Gastroenterology. 1977 Apr;72(4 Pt.2):803-10.  

[2]. Chappa AK, et al. Characteristics of substance P transport across the blood-brain barrier. Pharm Res. 2006 Jun;23(6):1201-8.  

Chemical & Physical Properties

Molecular FormulaC57H86N14O12S
Molecular Weight1191.44000
Exact Mass1190.63000
PSA445.73000
LogP3.86420
InChIKeyHGUMOPZYRIFNRE-UHFFFAOYSA-N
SMILESCSCCC(NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)NC(=O)C(CCC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C1CCCN1C(=O)C(CCCCN)NC(=O)C1CCCN1)C(N)=O

Synonyms

Substance-P-(2-11)Deca-Substance P
H-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2
SUBSTANCE P(2-11) TRIFLUOROACETATE SALT (DECA-SUBSTANCE P,SP
PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2
DECA-SUBSTANCE P
Substance P,fragment 2-11
substance P fragment 2-11 acetate
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