Introduction：Basic information about CAS 21392-57-4|Chrysin dimethylether, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Chrysin dimethylether |
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| CAS Number | 21392-57-4 | Molecular Weight | 282.291 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 476.6±45.0 °C at 760 mmHg |
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| Molecular Formula | C17H14O4 | Melting Point | 150-152ºC |
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| MSDS | / | Flash Point | 213.4±28.8 °C |
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Names
| Name | chrysin 5,7-dimethyl ether |
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| Synonym | More Synonyms |
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Chrysin dimethylether BiologicalActivity
| Description | 5,7-Dimethoxyflavone is one of the major components of Kaempferia parviflora, has anti-obesity, anti-inflammatory, and antineoplastic effects. 5,7-Dimethoxyflavone inhibits cytochrome P450 (CYP) 3As. 5,7-Dimethoxyflavone is also a potent Breast Cancer Resistance Protein (BCRP) inhibitor[1][2]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Metabolic Enzyme/Protease >>Cytochrome P450Research Areas >>Inflammation/Immunology |
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| Target | CYP3A Breast Cancer Resistance Protein (BCRP) |
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| References | [1]. Ochiai W, et al. Effect of the active ingredient of Kaempferia parviflora, 5,7-dimethoxyflavone, on the pharmacokinetics of midazolam. J Nat Med. 2018 Jun;72(3):607-614. [2]. Bae S, et al. Effect of 5,7-dimethoxyflavone on Bcrp1-mediated transport of sorafenib in vitro and in vivo in mice. Eur J Pharm Sci. 2018 May 30;117:27-34. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 476.6±45.0 °C at 760 mmHg |
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| Melting Point | 150-152ºC |
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| Molecular Formula | C17H14O4 |
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| Molecular Weight | 282.291 |
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| Flash Point | 213.4±28.8 °C |
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| Exact Mass | 282.089203 |
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| PSA | 48.67000 |
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| LogP | 3.27 |
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| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
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| Index of Refraction | 1.598 |
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| InChIKey | JRFZSUMZAUHNSL-UHFFFAOYSA-N |
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| SMILES | COc1cc(OC)c2c(=O)cc(-c3ccccc3)oc2c1 |
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Safety Information
Customs
| HS Code | 2914509090 |
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| Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
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Synonyms
| 5,7-dimethoxy-2-phenyl-4H-1-benzopyran-4-one |
| Dimethylchrysin |
| Chrysin DME |
| 5,7-dimethoxyflavonone |
| MFCD00016943 |
| 2-phenyl-5,7-dimethoxyl-flavone |
| 4H-1-Benzopyran-4-one,5,7-dimethoxy-2-phenyl |
| Chrysin 5,7-dimethyl ether |
| 4H-1-Benzopyran-4-one, 5,7-dimethoxy-2-phenyl- |
| 5,7-DIMETHOXYFLAVONE |
| 5,7-dimethoxy-2-phenylchromen-4-one |
| 5,7-dimethoxycrysin |
| 5,7-dimethoxy-2-phenyl-chromen-4-one |
| 5,7-Dimethoxy-2-phenyl-4H-chromen-4-one |
| Chrysindimethylether |
| Chrysin dimethylether |
