Introduction：Basic information about CAS 117678-38-3|Levofloxacin N-oxide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Levofloxacin N-oxide |
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| CAS Number | 117678-38-3 | Molecular Weight | 377.367 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C18H20FN3O5 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Levofloxacin N-oxide |
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| Synonym | More Synonyms |
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Levofloxacin N-oxide BiologicalActivity
| Description | Levofloxacin N-oxide is a minor metabolite of Levofloxacin (HY-B0330). Levofloxacin N-oxide does not exhibit significantly genotoxic risks. Levofloxacin is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria[1][2]. |
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| Related Catalog | Research Areas >>Infection |
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| References | [1]. Zhu Q, et al. In silico and in vitro genotoxicity evaluation of levofloxacin n-oxide, an impurity in levofloxacin. Toxicol Mech Methods. 2012 Apr;22(3):225-30. [2]. Nightingale CH, et al. Pharmacodynamics and pharmacokinetics of levofloxacin. Chemotherapy. 2000;46 Suppl 1:6-14. |
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Chemical & Physical Properties
| Molecular Formula | C18H20FN3O5 |
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| Molecular Weight | 377.367 |
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| Exact Mass | 377.138702 |
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| PSA | 101.20000 |
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| LogP | -1.03 |
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| InChIKey | MVLAUMUQGRQERL-JTQLQIEISA-N |
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| SMILES | CC1COc2c(N3CC[N+](C)([O-])CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23 |
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Synonyms
| unii-ue0e2o42uc |
| (3S)-9-Fluoro-3-methyl-10-(4-methyl-4-oxido-1-piperazinyl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid |
| 7H-1,4-Oxazino[2,3,4-ij]quinoline-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-4-oxido-1-piperazinyl)-7-oxo-, (3S)- |
| Levofloxacin Impurity 1 |
