CAS 117707-40-1|N-Desmethyl levofloxacin

Introduction：Basic information about CAS 117707-40-1|N-Desmethyl levofloxacin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. N-Desmethyl levofloxacin BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Articles1
6. Synonyms

Common Name	N-Desmethyl levofloxacin
CAS Number	117707-40-1	Molecular Weight	347.34100
Density	1.517g/cm3	Boiling Point	600.714ºC at 760 mmHg
Molecular Formula	C₁₇H₁₈FN₃O₄	Melting Point	/
MSDS	/	Flash Point	317.101ºC
Symbol	GHS07	Signal Word	Warning

Names

Name	S-(-)-9-fluoro-2,3-dihydro-3-methyl-10-(1-piperazinyl)-7-oxo-7H-pyrido-<1,2,3-de><1,4>benzoxazine-6-carboxylic acid
Synonym	More Synonyms

N-Desmethyl levofloxacin BiologicalActivity

Description	Desmethyl Levofloxacin is a metabolite of Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication[1].
Related Catalog	Research Areas >>Infection
References	[1]. Siva, R., et al., Effect of levofloxacin on neutrophilic airway inflammation in stable COPD: a randomized, double-blind, placebo-controlled trial. Int J Chron Obstruct Pulmon Dis, 2014. 9: p. 179-86.

Chemical & Physical Properties

Density	1.517g/cm3
Boiling Point	600.714ºC at 760 mmHg
Molecular Formula	C₁₇H₁₈FN₃O₄
Molecular Weight	347.34100
Flash Point	317.101ºC
Exact Mass	347.12800
PSA	83.80000
LogP	1.59560
Vapour Pressure	0mmHg at 25°C
Index of Refraction	1.677
InChIKey	WKRSSAPQZDHYRV-VIFPVBQESA-N
SMILES	CC1COc2c(N3CCNCC3)c(F)cc3c(=O)c(C(=O)O)cn1c23

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Hazard Codes	Xn
Risk Phrases	22
RIDADR	NONH for all modes of transport

Articles1

Pharmacokinetics and pharmacodynamics of fluoroquinolones. Rodvold, Keith A., and Melinda Neuhauser.

Pharmacotherapy 21.10P2 , 233S-252S, (2001)

Synonyms

UNII-88ZBA45NC8

Levofloxacin related compound A

Uing 4-255

des-methyl levofloxacin

N-Desmethyl levofloxacin

Levofloxacin Impurity 2

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