Introduction：Basic information about CAS 110522-74-2|2'-Deoxy-N6-phenoxyacetyladenosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2'-Deoxy-N6-phenoxyacetyladenosine |
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| CAS Number | 110522-74-2 | Molecular Weight | 385.37 |
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| Density | 1.58±0.1 g/cm3(Predicted) | Boiling Point | / |
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| Molecular Formula | C18H19N5O5 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | N-[9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]-2-phenoxyacetamide |
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| Synonym | More Synonyms |
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2'-Deoxy-N6-phenoxyacetyladenosine BiologicalActivity
| Description | 2'-Deoxy-N6-phenoxyacetyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.58±0.1 g/cm3(Predicted) |
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| Molecular Formula | C18H19N5O5 |
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| Molecular Weight | 385.37 |
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| Exact Mass | 385.13900 |
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| PSA | 131.62000 |
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| LogP | 0.55750 |
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| InChIKey | HWSKJANFAKYDDL-GZBFAFLISA-N |
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| SMILES | O=C(COc1ccccc1)Nc1ncnc2c1ncn2C1CC(O)C(CO)O1 |
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| Storage condition | -20℃ |
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Synonyms
| N-phenoxyacetyl-2'-deoxyadenosine |
| 2'-Deoxy-N6-phenoxyacetyladenosine |
| N6-phenoxyacetyl-2'-deoxyadenosine |
