CAS 35575-96-3|Azamethiphos
| Common Name | Azamethiphos | ||
|---|---|---|---|
| CAS Number | 35575-96-3 | Molecular Weight | 324.678 |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 428.8±55.0 °C at 760 mmHg |
| Molecular Formula | C9H10ClN2O5PS | Melting Point | 88-93°C |
| MSDS | ChineseUSA | Flash Point | 213.1±31.5 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | azamethiphos |
|---|---|
| Synonym | More Synonyms |
Azamethiphos BiologicalActivity
| Description | Azamethiphos is an organophosphate insecticide and a neurotoxic agent, causing acetylcholinesterase (AChE) inhibition[1]. |
|---|---|
| Related Catalog | Research Areas >>Neurological DiseaseSignaling Pathways >>Neuronal Signaling >>AChE |
| References | [1]. Barisic J, et al. Cumulative impact of anti-sea lice treatment (azamethiphos) on health status of Rainbow trout (Oncorhynchus mykiss, Walbaum 1792) in aquaculture [published correction appears in Sci Rep. 2020 May 20;10(1):8643]. Sci Rep. 2019;9(1):16217. Published 2019 Nov 7. |
Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 428.8±55.0 °C at 760 mmHg |
| Melting Point | 88-93°C |
| Molecular Formula | C9H10ClN2O5PS |
| Molecular Weight | 324.678 |
| Flash Point | 213.1±31.5 °C |
| Exact Mass | 323.973663 |
| PSA | 118.67000 |
| LogP | 0.82 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.589 |
| InChIKey | VNKBTWQZTQIWDV-UHFFFAOYSA-N |
| SMILES | COP(=O)(OC)SCn1c(=O)oc2cc(Cl)cnc21 |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1180 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,44,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,44,1991
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R22;R36 |
| Safety Phrases | S26-S36/37-S24/25-S23 |
| RIDADR | UN 1593 6.1/PG 3 |
| RTECS | TE8070000 |
Articles28
More Articles| Albumin binding as a potential biomarker of exposure to moderately low levels of organophosphorus pesticides. Biol. Cell 13 , 343-63, (2008) We have evaluated the potential of plasma albumin to provide a sensitive biomarker of exposure to commonly used organophosphorus pesticides in order to complement the widely used measure of acetylchol... | |
| Evaluation of insecticidal efficiency of certain new selective formulations against Musca domestica (L). J. Egypt. Soc. Parasitol. 22(3) , 839-49, (1992) Five new selective formulations were tested for effectiveness, applicability and costs in controlling the housefly Musca domestica. The tested formulations are Alfacron SB, Alfacron 10 WP, Snip IRB (a... | |
| Characterisation of esterases as potential biomarkers of pesticide exposure in the lugworm Arenicola marina (Annelida: Polychaeta). Environ. Pollut. 152(2) , 342-50, (2008) Here, we identify and characterise cholinesterase (ChE) and carboxylesterase (CbE) activities in the body tissues of the sediment dwelling worm Arenicola marina. Exposure to the organophosphorus pesti... |
Synonyms
| azametifos |
| EINECS 252-626-0 |
| Alfracron |
| S-[(6-chloro-2-oxo-1,3-oxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O-dimethyl phosphorothioate |
| S-[(6-Chloro-2-oxo[1,3]oxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O-dimethyl phosphorothioate |
| MFCD00867611 |
| S-[(6-Chloro-2-oxooxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O-Dimethyl Phosphorothioate |
| snip |
| ALFACRON |
| Azamethiphos |
| S-[(6-Chlor-2-oxo[1,3]oxazolo[4,5-b]pyridin-3(2H)-yl)methyl]-O,O-dimethylthiophosphat |
| Salmosan |
| Phosphorothioic acid, S-[(6-chloro-2-oxooxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O-dimethyl ester |
| S-6-Chloro-2,3-dihydro-2-oxo-1,3-oxazolo[4,5-b]pyridin-3-ylmethyl O,O-Dimethyl Phosphorothioate |
