CAS 68370-47-8|Micheliolide

Introduction：Basic information about CAS 68370-47-8|Micheliolide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Micheliolide BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Micheliolide
CAS Number	68370-47-8	Molecular Weight	248.318
Density	1.2±0.1 g/cm3	Boiling Point	426.1±45.0 °C at 760 mmHg
Molecular Formula	C₁₅H₂₀O₃	Melting Point	/
MSDS	/	Flash Point	181.8±21.5 °C

Names

Name	(3aS,9R,9aS,9bS)-9-hydroxy-6,9-dimethyl-3-methylidene-4,5,7,8,9a,9b-hexahydro-3aH-azuleno[4,5-b]furan-2-one
Synonym	More Synonyms

Micheliolide BiologicalActivity

Description	Micheliolide could effectively attenuate the high glucose-stimulated activation of NF-κB, the degradation of IκBα, and the expression of MCP-1, TGF-β1 and FN in rat mesangial cells (MCs).
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>OthersNatural Products >>Terpenoids and Glycosides
References	[1]. Jia QQ, et al. Sesquiterpene lactones and their derivatives inhibit high glucose-induced NF-κB activation and MCP-1 and TGF-β1 expression in rat mesangial cells. Molecules. 2013 Oct 21;18(10):13061-77.

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	426.1±45.0 °C at 760 mmHg
Molecular Formula	C₁₅H₂₀O₃
Molecular Weight	248.318
Flash Point	181.8±21.5 °C
Exact Mass	248.141251
PSA	46.53000
LogP	2.14
Vapour Pressure	0.0±2.3 mmHg at 25°C
Index of Refraction	1.555
InChIKey	RDJAFOWISVMOJY-PWNZVWSESA-N
SMILES	C=C1C(=O)OC2C1CCC(C)=C1CCC(C)(O)C12
Storage condition	-20°C

Synonyms

Azuleno[4,5-b]furan-2(3H)-one, 3a,4,5,7,8,9,9a,9b-octahydro-9-hydroxy-6,9-dimethyl-3-methylene-, (3aS,9R,9aS,9bS)-

(3aS,9R,9aS,9bS)-9-Hydroxy-6,9-dimethyl-3-methylene-3a,4,5,7,8,9,9a,9b-octahydroazuleno[4,5-b]furan-2(3H)-one

Mecheliolide

MICHELIOLIDE

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