Introduction：Basic information about CAS 878143-33-0|Dolasetron (Mesylate hydrate), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Dolasetron (Mesylate hydrate) |
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| CAS Number | 878143-33-0 | Molecular Weight | 438.49 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C20H26N2O7S | Melting Point | 178 °C |
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| MSDS | / | Flash Point | / |
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Names
| Name | UNII-U3C8E5BWKR component QTFFGPOXNNGTGZ-BEQIPBGHSA-M |
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| Synonym | More Synonyms |
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Dolasetron (Mesylate hydrate) BiologicalActivity
| Description | Dolasetron(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>5-HT ReceptorSignaling Pathways >>Neuronal Signaling >>5-HT ReceptorResearch Areas >>Others |
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| References | [1]. Faria C, et al. Outcomes Associated with 5-HT3-RA Therapy Selection in Patients with Chemotherapy-Induced Nausea and Vomiting: A Retrospective Claims Analysis. Am Health Drug Benefits. 2014 Jan;7(1):50-8. [2]. Schwartzberg L, et al. Pooled analysis of phase III clinical studies of palonosetron versus ondansetron, dolasetron, and granisetron in the prevention of chemotherapy-induced nausea and vomiting (CINV). Support Care Cancer. 2014 Feb;22(2):469-77. |
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Chemical & Physical Properties
| Melting Point | 178 °C |
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| Molecular Formula | C20H26N2O7S |
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| Molecular Weight | 438.49 |
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| PSA | 137.21000 |
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| LogP | 2.63480 |
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| InChIKey | QTFFGPOXNNGTGZ-RCSCTSIBSA-N |
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| SMILES | CS(=O)(=O)O.O.O=C(OC1CC2CC3CC(C1)N2CC3=O)c1c[nH]c2ccccc12 |
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Synonyms
| Dolasetron (Mesylate hydrate) |
