CAS 30674-80-7|2-Isocyanatoethyl methacrylate

Introduction：Basic information about CAS 30674-80-7|2-Isocyanatoethyl methacrylate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles23
7. Synonyms

Common Name	2-Isocyanatoethyl methacrylate
CAS Number	30674-80-7	Molecular Weight	155.151
Density	1.0±0.1 g/cm3	Boiling Point	218.8±23.0 °C at 760 mmHg
Molecular Formula	C₇H₉NO₃	Melting Point	-45ºC
MSDS	ChineseUSA	Flash Point	92.5±17.1 °C
Symbol	GHS06, GHS08	Signal Word	Danger

Names

Name	2-isocyanatoethyl 2-methylprop-2-enoate
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.0±0.1 g/cm3
Boiling Point	218.8±23.0 °C at 760 mmHg
Melting Point	-45ºC
Molecular Formula	C₇H₉NO₃
Molecular Weight	155.151
Flash Point	92.5±17.1 °C
Exact Mass	155.058243
PSA	55.73000
LogP	2.27
Vapour Pressure	0.1±0.4 mmHg at 25°C
Index of Refraction	1.456
InChIKey	RBQRWNWVPQDTJJ-UHFFFAOYSA-N
SMILES	C=C(C)C(=O)OCCN=C=O
Storage condition	2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OZ4950000

CHEMICAL NAME :: Metharcylic acid, 2-isocyanatoethyl ester

CAS REGISTRY NUMBER :: 30674-80-7

BEILSTEIN REFERENCE NO. :: 1768533

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C7-H9-N-O3

MOLECULAR WEIGHT :: 155.17

WISWESSER LINE NOTATION :: OCN2OVY1&U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 670 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 3,381,1980

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4 ppm/6H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 3,381,1980 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1 ppm/6H/10D-I

TOXIC EFFECTS :: Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Blood - changes in leukocyte (WBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0528752 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 80 ppb/6H

SEX/DURATION :: male 49 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

REFERENCE :: DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 3,381,1980

Safety Information

Symbol	GHS06, GHS08
Signal Word	Danger
Hazard Statements	H302-H315-H317-H319-H330-H334-H335
Precautionary Statements	P260-P280-P284-P305 + P351 + P338-P310
Hazard Codes	T+:Verytoxic;
Risk Phrases	R21/22;R26;R37/38;R41;R42
Safety Phrases	S26-S36/37/39-S45
RIDADR	UN 2206
WGK Germany	3
RTECS	OZ4950000
Packaging Group	II
Hazard Class	6.1(a)
HS Code	2929109000

Customs

HS Code	2929109000
Summary	2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles23

Construction of monomer-free, highly crosslinked, water-compatible polymers.

J. Dent. Res. 93(12) , 1326-31, (2014)

Polymeric dental adhesives require the formation of densely crosslinked network structures to best ensure mechanical strength and durability in clinical service. Monomeric precursors to these material...

Galectin-3 binding protein links circulating microparticles with electron dense glomerular deposits in lupus nephritis.

Lupus 24 , 1150-60, (2015)

A high level of galectin-3-binding protein (G3BP) appears to distinguish circulating cell-derived microparticles in systemic lupus erythematosus (SLE). The aim of this study is to characterize the pop...

Synthesis of antibacterial methacrylate monomer derived from thiazole and its application in dental resin.

J. Mech. Behav. Biomed. Mater. 49 , 61-8, (2015)

A non-quaternary ammonium antibacterial methacrylate monomer MEMT derived from thiazole was synthesized and applied into UDMA/TEGDMA dental resin with a series of mass fraction (10 wt%, 20 wt%, and 30...

Synonyms

2-Isocyanatoethyl 2-methylacrylate

2-Isocyanatoethyl methacrylate

METHACRYLOYLOXYETHYL ISOCYANATE

Methacrylic Acid 2-Isocyanatoethyl Ester

2-Propenoic acid, 2-methyl-, 2-isocyanatoethyl ester

EINECS 250-284-7

2-(Methacryloyloxy)ethyl Isocyanate

Isocyanoethyl methacrylate

2-(Methacryloyloxy)ethyl isocyanate,IEM

MFCD00080536

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