CAS 128-09-6|N-chlorosuccinimide

Introduction:Basic information about CAS 128-09-6|N-chlorosuccinimide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameN-chlorosuccinimide
CAS Number128-09-6Molecular Weight133.533
Density1.5±0.1 g/cm3Boiling Point200.5±23.0 °C at 760 mmHg
Molecular FormulaC4H4ClNO2Melting Point148-150 °C(lit.)
MSDSChineseUSAFlash Point75.1±22.6 °C
Symbol
GHS05, GHS07
Signal WordDanger

Names

NameN-chlorosuccinimide
SynonymMore Synonyms

Chemical & Physical Properties

Density1.5±0.1 g/cm3
Boiling Point200.5±23.0 °C at 760 mmHg
Melting Point148-150 °C(lit.)
Molecular FormulaC4H4ClNO2
Molecular Weight133.533
Flash Point75.1±22.6 °C
Exact Mass132.993057
PSA37.38000
LogP-0.87
Vapour Pressure0.3±0.4 mmHg at 25°C
Index of Refraction1.532
InChIKeyJRNVZBWKYDBUCA-UHFFFAOYSA-N
SMILESO=C1CCC(=O)N1Cl

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UY1013500
CHEMICAL NAME :
2,5-Pyrrolidinedione, 1-chloro-
CAS REGISTRY NUMBER :
128-09-6
BEILSTEIN REFERENCE NO. :
0113915
LAST UPDATED :
199701
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C4-H4-Cl-N-O2
MOLECULAR WEIGHT :
133.54
WISWESSER LINE NOTATION :
T5VNVTJ BG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PHRPA6 Public Health Reports. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1878- Volume(issue)/page/year: 59,541,1944
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - chronic pulmonary edema Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
PHRPA6 Public Health Reports. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1878- Volume(issue)/page/year: 59,541,1944 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
15 gm/kg/40D-C
TOXIC EFFECTS :
Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
REFERENCE :
PHRPA6 Public Health Reports. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1878- Volume(issue)/page/year: 59,541,1944
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
5800 mg/kg/5W-I
TOXIC EFFECTS :
Blood - pigmented or nucleated red blood cells
REFERENCE :
PHRPA6 Public Health Reports. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1878- Volume(issue)/page/year: 59,541,1944 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
840 mg/kg/70W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
REFERENCE :
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 53,695,1974

Safety Information

Symbol
GHS05, GHS07
Signal WordDanger
Hazard StatementsH302-H314
Precautionary StatementsP280-P305 + P351 + P338-P310
Personal Protective EquipmentEyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard CodesC:Corrosive
Risk PhrasesR22;R34
Safety PhrasesS26-S36/37/39-S45-S37/39
RIDADRUN 3261 8/PG 2
WGK Germany3
RTECSUY1013500
Packaging GroupIII
Hazard Class8
HS Code2933990090

Customs

HS Code2925190090
Summary2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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Synonyms

succinimide, N-chloro-
Chlorosuccinimide
EINECS 204-878-8
N-chlorobutanimide
1-Chloro-2,5-pyrrolidinedione
2,5-Pyrrolidinedione, 1-chloro-
Succinimide, N-chloro- (8CI)
1-chloropyrrolidine-2,5-dione
N-Chlorosuccinimide
MFCD00005511
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