Introduction：Basic information about CAS 38594-96-6|(R)?-?PIA, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
(-)-N6-phenylisopropyl adenosine (D-phenylisopropyladenosine) is a adenosine receptor agonist. (-)-N6-phenylisopropyl adenosine inhibits K+-evoked Ca2+ uptake with an IC50 value of 0.5 µM[1].
Related Catalog
Research Areas >>Neurological DiseaseSignaling Pathways >>GPCR/G Protein >>Adenosine Receptor
References
[1]. Wu PH, et al. Adenosine receptor agonists inhibit K+-evoked Ca2+ uptake by rat brain cortical synaptosomes. J Neurochem. 1982 Sep;39(3):700-8.
Chemical & Physical Properties
Density
1.506g/cm3
Boiling Point
675.716ºC at 760 mmHg
Molecular Formula
C19H23N5O4
Molecular Weight
385.42
Flash Point
362.46ºC
Exact Mass
385.17500
PSA
125.55000
LogP
0.55390
Index of Refraction
1.712
InChIKey
RIRGCFBBHQEQQH-SSFGXONLSA-N
SMILES
CC(Cc1ccccc1)Nc1ncnc2c1ncn2C1OC(CO)C(O)C1O
Toxicological Information
CHEMICAL IDENTIFICATION
RTECS NUMBER :
AU7404930
CHEMICAL NAME :
Adenosine, N-(1-methyl-2-phenylethyl)-, (R)-
CAS REGISTRY NUMBER :
38594-96-6
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C19-H23-N5-O4
MOLECULAR WEIGHT :
385.47
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
770 ug/kg
SEX/DURATION :
female 11-12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 25(2),35A,1982
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