CAS 80-59-1|Tiglic acid
Introduction：Basic information about CAS 80-59-1|Tiglic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Tiglic acid | ||
|---|---|---|---|
| CAS Number | 80-59-1 | Molecular Weight | 100.116 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 198.5±0.0 °C at 760 mmHg |
| Molecular Formula | C5H8O2 | Melting Point | 61-64 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 95.9±9.6 °C |
| Symbol | GHS05 | Signal Word | Danger |
Names
| Name | tiglic acid |
|---|---|
| Synonym | More Synonyms |
Tiglic acid BiologicalActivity
| Description | Tiglic acid is a monocarboxylic unsaturated organic acid found in croton oil and in several other natural products. Tiglic aci has a role as a plant metabolite[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. ROBERT E. BUCKLES, et al. THE PREPARATION OF TIGLIC AND ANGELIC ACIDS AND ESTERS. Cite This:J. Org. Chem.1950153680-684. |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 198.5±0.0 °C at 760 mmHg |
| Melting Point | 61-64 °C(lit.) |
| Molecular Formula | C5H8O2 |
| Molecular Weight | 100.116 |
| Flash Point | 95.9±9.6 °C |
| Exact Mass | 100.052429 |
| PSA | 37.30000 |
| LogP | 1.35 |
| Vapour Pressure | 0.2±0.7 mmHg at 25°C |
| Index of Refraction | 1.451 |
| InChIKey | UIERETOOQGIECD-ONEGZZNKSA-N |
| SMILES | CC=C(C)C(=O)O |
| Storage condition | Refrigerator (+4°C) |
| Water Solubility | SOLUBLE IN HOT WATER |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,837,1982 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,837,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,837,1982
Safety Information
| Symbol | GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H314 |
| Precautionary Statements | P280-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36/37/39-S45-S24/25 |
| RIDADR | UN 3261 8/PG 2 |
| WGK Germany | 2 |
| RTECS | GQ5430000 |
| Packaging Group | III |
| Hazard Class | 8 |
| HS Code | 29161980 |
Customs
| HS Code | 29161980 |
|---|
Articles14
More Articles| Largamides A-C, tiglic acid-containing cyclodepsipeptides with elastase-inhibitory activity from the marine cyanobacterium Lyngbya confervoides. Planta Med. 75 , 528-33, (2009) Three unusual tiglic acid-containing cyclodepsipeptides, possessing the revised regioisomeric structures for largamides A-C (1-3), have been isolated from the marine cyanobacterium Lyngbya confervoide... | |
| Pathway of formation of branched-chain volatile fatty acids in Ascaris mitochondria. J. Parasitol. 67(6) , 841-6, (1981) Disrupted Ascaris mitochondria formed 2-methylbutyrate (2-MB) and 2-methylvalerate (2-MV) when incubated anaerobically with acetyl CoA, propionyl CoA and NADH. However, when mitochondrial membranes we... | |
| Biosynthesis of tiglic, ethacrylic, and 2-methylbutyric acids in a carabid beetle, Pterostichus (Hypherpes) californicus. J. Chem. Ecol. 33(5) , 963-70, (2007) Tiglic, 2-methylbutyric, and ethacrylic acids are found in the pygidial gland defensive fluid of many carabid beetles. By injecting a deuterium-labeled precursor into the carabid beetle Pterostichus (... |
Synonyms
| (2E)-2-Methyl-2-butenoic acid |
| 2-Butenoic acid, 2-methyl-, (2E)- |
| FEMA 3599 |
| 2,3-Dimethylacrylic acid |
| EINECS 201-295-0 |
| (2E)-2-Methylbut-2-enoic acid |
| Cevadic acid |
| Tiglic acid |
| E-Tiglic acid |
| MFCD00066864 |
| Tiglate |
| (E)-2-methyl-2-butenoic acid |
