CAS 2642-71-9|Azinphos-ethyl

Introduction：Basic information about CAS 2642-71-9|Azinphos-ethyl, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Articles7
6. Synonyms

Common Name	Azinphos-ethyl
CAS Number	2642-71-9	Molecular Weight	345.378
Density	1.4±0.1 g/cm3	Boiling Point	444.7±55.0 °C at 760 mmHg
Molecular Formula	C₁₂H₁₆N₃O₃PS₂	Melting Point	53ºC
MSDS	ChineseUSA	Flash Point	222.7±31.5 °C
Symbol	GHS06, GHS09	Signal Word	Danger

Names

Name	azinphos-ethyl
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	444.7±55.0 °C at 760 mmHg
Melting Point	53ºC
Molecular Formula	C₁₂H₁₆N₃O₃PS₂
Molecular Weight	345.378
Flash Point	222.7±31.5 °C
Exact Mass	345.037079
PSA	133.44000
LogP	3.61
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.651
InChIKey	RQVGAIADHNPSME-UHFFFAOYSA-N
SMILES	CCOP(=S)(OCC)SCn1nnc2ccccc2c1=O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TD8400000

CHEMICAL NAME :: Phosphorodithioic acid, O,O-diethyl ester, S-ester with 3-(mercaptomethyl)- 1,2,3-benzotriazin-4(3H)-one

CAS REGISTRY NUMBER :: 2642-71-9

BEILSTEIN REFERENCE NO. :: 0297468

LAST UPDATED :: 199710

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C12-H16-N3-O3-P-S2

MOLECULAR WEIGHT :: 345.40

WISWESSER LINE NOTATION :: T66 BNNNVJ D1SPS&O2&O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARSIM* Agricultural Research Service, USDA Information Memorandum. (Beltsville, MD 20705) Volume(issue)/page/year: 20,2,1966

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 390 mg/m3

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GYAV "Pflanzenschutz-und Schaedlingsbekaempfungsmittel: Abriss einer Toxikologie und Therapie von Vergiftungen," 2nd ed., Klimmer, O.R., Hattingen, Fed. Rep. Ger., Hundt-Verlag, 1971 Volume(issue)/page/year: -,16,1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GUCHAZ Guide to the Chemicals Used in Crop Protection. (Information Canada, 171 Slater St., Ottawa, Ont., Canada) Volume(issue)/page/year: 6,24,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GUCHAZ Guide to the Chemicals Used in Crop Protection. (Information Canada, 171 Slater St., Ottawa, Ont., Canada) Volume(issue)/page/year: 6,24,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 12 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,45,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 34400 ug/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 11,49,1967 *** REVIEWS *** TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 51,123,1974 TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 63,1,1976

Safety Information

Symbol	GHS06, GHS09
Signal Word	Danger
Hazard Statements	H300-H311-H410
Precautionary Statements	P273-P280-P301 + P310 + P330-P302 + P352 + P312-P391-P501
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T+: Very toxic;N: Dangerous for the environment;
Risk Phrases	24-28-50/53
Safety Phrases	S28-S36/37-S45-S60-S61
RIDADR	2783
RTECS	TD8400000
Packaging Group	II
Hazard Class	6.1(a)

Articles7

Characterization of P-S bond hydrolysis in organophosphorothioate pesticides by organophosphorus hydrolase.

Arch. Biochem. Biophys. 318(1) , 59-64, (1995)

The extensive use of organophosphorothioate insecticides in agriculture has resulted in the risk of environmental contamination with a variety of broadly based neurotoxins that inhibit the acetylcholi...

Performance of two monoclonal immunoassays in mixtures of cross-reacting dithiophosphorus pesticides

Talanta 74(1) , 52-8, (2007)

A statistical approach for the analysis of complex samples by immunoassay is proposed in this article. Two enzyme-linked immunosorbent assays (ELISAs), one of them in the conjugate-coated format and t...

Ethylazinphos interaction with membrane lipid organization induces increase of proton permeability and impairment of mitochondrial bioenergetic functions.

Toxicol. Appl. Pharmacol. 175(3) , 209-16, (2001)

Ethylazinphos increases the passive proton permeability of lipid bilayers reconstituted with dipalmitoylphosphatidylcholine (DPPC) and mitochondrial lipids. A sharp increase of proton permeability is ...

Synonyms

Dithiophosphate de O,O-diéthyle et de S-[(4-oxo-1,2,3-benzotriazin-3(4H)-yl)méthyle]

azinfos-ethyl

Gutex

triazothion

Azinphos-ethyl

Gusathion H & K

Athyl-gusathion

O,O-Diethyl S-((4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl) phosphorodithioate (9CI)

Gusathion

Ethyl-Gusathion

Azinphosethyl

O,O-Diethyl-S-[(4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl]dithiophosphat

Crysthion

Azinphos-ethyl PESTANAL(R),analytical standard

EINECS 220-147-6

O,O-Diethyl S-[(4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl] phosphorodithioate

Azinophos-ethyl

Bionex

S-3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-ylmethyl O,O-diethyl phosphorodithioate

Ethyl azinphos

Azinphos ethyl

MFCD00055539

O,O-diethyl S-<(4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl> phosphorodithioate

O,O-diethyl-S(3,4-dihydro-4-oxobenzo<d><1,2,3>triazin-3-yl-methyl)phosphorodithioate

Phosphorodithioic acid, O,O-diethyl S-[(4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl] ester

Azinos

3-(diethoxyphosphinothioylsulfanylmethyl)-1,2,3-benzotriazin-4-one

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