Introduction：Basic information about CAS 53839-71-7|Viaminate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Viaminate |
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| CAS Number | 53839-71-7 | Molecular Weight | 447.61 |
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| Density | 1.071 g/cm3 | Boiling Point | 619.4ºCat 760 mmHg |
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| Molecular Formula | C29H37NO3 | Melting Point | 177-182 °C |
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| MSDS | / | Flash Point | 328.4ºC |
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Names
| Name | ethyl 4-[[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoyl]amino]benzoate |
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| Synonym | More Synonyms |
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Viaminate BiologicalActivity
| Description | Viaminate is a derivative of Retinoic acid, which is used for the treatment of severe acne and other keratinization disorders. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| In Vitro | Viaminate is an amide compound formed by Tretinoin and Ethyl p-aminobenzoate, in which the end group of Tretinoin is transformed into amide and ester chain[1]. |
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| References | [1]. Zhang H, et al. Fatal Hepatotoxicity Due to Viaminate. Am J Med Sci. 2018 Jul;356(1):84-86. |
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Chemical & Physical Properties
| Density | 1.071 g/cm3 |
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| Boiling Point | 619.4ºCat 760 mmHg |
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| Melting Point | 177-182 °C |
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| Molecular Formula | C29H37NO3 |
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| Molecular Weight | 447.61 |
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| Flash Point | 328.4ºC |
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| Exact Mass | 447.27700 |
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| PSA | 55.40000 |
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| LogP | 7.40640 |
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| InChIKey | VRSMJNVXOITYPE-FSDIUQKZSA-N |
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| SMILES | CCOC(=O)c1ccc(NC(=O)C=C(C)C=CC=C(C)C=CC2=C(C)CCCC2(C)C)cc1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- VH6409600
- CHEMICAL NAME :
- Retinamide, N-(4-(ethoxycarbonyl)phenyl)-
- CAS REGISTRY NUMBER :
- 53839-71-7
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C29-H37-N-O3
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year: 17,331,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 8806 mg/kg/2W-I
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year: 17,331,1982
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Safety Information
Synonyms
| N-(4-(Ethoxycarbonyl)phenyl)retinamide |
| viaminate |
| 4-(Ethoxycarbophenyl)retinamide |
| 4-(Carboethoxyphenyl)retinamide |
| retinamide ethyl benzoate |
| Retinamide,N-(4-(ethoxycarbonyl)phenyl) |
