Introduction：Basic information about CAS 86393-33-1|7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
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| CAS Number | 86393-33-1 | Molecular Weight | 281.667 |
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| Density | 1.7±0.1 g/cm3 | Boiling Point | 467.3±45.0 °C at 760 mmHg |
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| Molecular Formula | C13H9ClFNO3 | Melting Point | 242-245 °C(lit.) |
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| MSDS | ChineseUSA | Flash Point | 236.4±28.7 °C |
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| Symbol |
GHS07 | Signal Word | Warning |
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Names
| Name | 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | Fluoroquinolonic acid is a bacteriostatic antibiotic. Fluoroquinolonic acid has broad-spectrum activity against Gram-positive and Gram-negative bacteria[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
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| Boiling Point | 467.3±45.0 °C at 760 mmHg |
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| Melting Point | 242-245 °C(lit.) |
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| Molecular Formula | C13H9ClFNO3 |
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| Molecular Weight | 281.667 |
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| Flash Point | 236.4±28.7 °C |
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| Exact Mass | 281.025513 |
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| PSA | 59.30000 |
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| LogP | 2.16 |
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| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
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| Index of Refraction | 1.683 |
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| InChIKey | ISPVACVJFUIDPD-UHFFFAOYSA-N |
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| SMILES | O=C(O)c1cn(C2CC2)c2cc(Cl)c(F)cc2c1=O |
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| Storage condition | -20°C Freezer |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- VB1993795
- CHEMICAL NAME :
- 3-Quinolinecarboxylic acid, 1,4-dihydro-7-chloro-1-cyclopropyl-6-fluoro-4-oxo-
- CAS REGISTRY NUMBER :
- 86393-33-1
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C13-H9-Cl-F-N-O3
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 583 mg/kg
- TOXIC EFFECTS :
- Skin and Appendages - hair
- REFERENCE :
- ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 15(Suppl 1),S96,1996
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >677 mg/m3/4H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 15(Suppl 1),S96,1996
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 15(Suppl 1),S96,1996
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Safety Information
| Symbol |
GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H302-H412 |
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| Precautionary Statements | P273 |
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| Hazard Codes | Xn:Harmful; |
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| Risk Phrases | R22;R52/53 |
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| Safety Phrases | S26-S36-S61-S22 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 2 |
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| RTECS | VB1993795 |
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| HS Code | 2933499090 |
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Customs
| HS Code | 2918300090 |
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| Summary | 2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
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Articles1
More Articles
| -Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid. Song J, et al. Acta Crystallogr. Sect. E Struct. Rep. Online 60(4) , o503-o504, (2004)
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Synonyms
| 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid |
| 3-Quinolinecarboxylic acid, 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo- |
| T66 BN EVJ DVQ HF IG B- AL3TJ |
| 7-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid |
| MFCD00792458 |
| 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
| 7-Chloro-1-cyclopropyl-6-fluoro-4-oxyhydroquinoline-3-carboxylic acid |
| EINECS 405-050-0 |
| 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-3-QUINOLINE CARBOXYLIC ACID |
