CAS 90134-00-2|Di-4-ANEPPS
| Common Name | Di-4-ANEPPS | ||
|---|---|---|---|
| CAS Number | 90134-00-2 | Molecular Weight | 480.66 |
| Density | / | Boiling Point | / |
| Molecular Formula | C28H36N2O3S | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | / |
Names
| Name | di-4-anepps |
|---|---|
| Synonym | More Synonyms |
Di-4-ANEPPS BiologicalActivity
| Description | Di-4-ANEPPS is a voltage-sensitive dye in membrane potential. Di-4-ANEPPS allows reaching a time resolution better than 1 ms and exhibits changes in fluorescence of up to 10% per 100 mV. Di-4-ANEPPS is a common tool for mapping cardiac electrical activity. Di-4-ANEPPS demonstrate significant direct irreversible effect on spontaneous heart rate and ventricular impulse conduction in rabbit isolated heart model[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. Marina Ronzhina, et al. Di-4-ANEPPS Modulates Electrical Activity and Progress of Myocardial Ischemia in Rabbit Isolated Heart. Front Physiol. 2021 Jun 10;12:667065. |
Chemical & Physical Properties
| Molecular Formula | C28H36N2O3S |
|---|---|
| Molecular Weight | 480.66 |
| Exact Mass | 480.24500 |
| PSA | 72.70000 |
| LogP | 6.72040 |
| InChIKey | HAPJROQJVSPKCJ-UHFFFAOYSA-N |
| SMILES | CCCCN(CCCC)c1ccc2cc(C=Cc3cc[n+](CCCS(=O)(=O)[O-])cc3)ccc2c1 |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
Articles32
More Articles| Effects of candesartan on electrical remodeling in the hearts of inherited dilated cardiomyopathy model mice. PLoS ONE 9(7) , e101838, (2014) Inherited dilated cardiomyopathy (DCM) is characterized by dilatation and dysfunction of the ventricles, and often results in sudden death or heart failure (HF). Although angiotensin receptor blockers... | |
| MeCP2 regulates the timing of critical period plasticity that shapes functional connectivity in primary visual cortex. Proc. Natl. Acad. Sci. U. S. A. 112 , E4782-91, (2015) Mutations in methyl-CpG-binding protein 2 (MeCP2) cause Rett syndrome, an autism spectrum-associated disorder with a host of neurological and sensory symptoms, but the pathogenic mechanisms remain elu... | |
| Long-Term Spatiotemporal Reconfiguration of Neuronal Activity Revealed by Voltage-Sensitive Dye Imaging in the Cerebellar Granular Layer. Neural Plast. 2015 , 284986, (2015) Understanding the spatiotemporal organization of long-term synaptic plasticity in neuronal networks demands techniques capable of monitoring changes in synaptic responsiveness over extended multineuro... |
Synonyms
| 4-(2-(6-(DIBUTYLAMINO)-2-NAPHTHALENYL)ETHENYL)-1-(3-SULFOPROPYL)PYRIDINIUM HYDROXIDE INNER SALT |
| MFCD03453609 |
| di-N-butylaminonaphthylethenylpyridiniumpropylsulfonate |
