CAS 14152-28-4|PROSTAGLANDIN A1
Introduction：Basic information about CAS 14152-28-4|PROSTAGLANDIN A1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | PROSTAGLANDIN A1 | ||
|---|---|---|---|
| CAS Number | 14152-28-4 | Molecular Weight | 336.466 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 510.7±50.0 °C at 760 mmHg |
| Molecular Formula | C20H32O4 | Melting Point | 41 - 43ºC |
| MSDS | ChineseUSA | Flash Point | 276.7±26.6 °C |
Names
| Name | prostaglandin A1 |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 510.7±50.0 °C at 760 mmHg |
| Melting Point | 41 - 43ºC |
| Molecular Formula | C20H32O4 |
| Molecular Weight | 336.466 |
| Flash Point | 276.7±26.6 °C |
| Exact Mass | 336.230072 |
| PSA | 74.60000 |
| LogP | 3.61 |
| Vapour Pressure | 0.0±3.0 mmHg at 25°C |
| Index of Refraction | 1.541 |
| InChIKey | BGKHCLZFGPIKKU-LDDQNKHRSA-N |
| SMILES | CCCCCC(O)C=CC1C=CC(=O)C1CCCCCCC(=O)O |
| Storage condition | −20°C |
| Water Solubility | acetone: 10 mg/mL, clear |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 12 mg/kg
- SEX/DURATION :
- male 10 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - other effects on male
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravaginal
- DOSE :
- 169 ug/kg
- SEX/DURATION :
- female 17 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravaginal
- DOSE :
- 169 ug/kg
- SEX/DURATION :
- female 17 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - urogenital system Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 10 mg/kg
- SEX/DURATION :
- female 16 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetal death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 40 mg/kg
- SEX/DURATION :
- female 16 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - abortion
MUTATION DATA - TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Human Cells - not otherwise specified
- DOSE/DURATION :
- 2500 ug/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 43,513,1983
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Human Cells - not otherwise specified
- DOSE/DURATION :
- 2500 ug/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 43,513,1983
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xn |
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | GY5977900 |
Articles38
More Articles| The cyclopentenone prostaglandin 15d-PGJ2 inhibits the NLRP1 and NLRP3 inflammasomes. J. Immunol. 194(6) , 2776-85, (2015) Inflammasomes are cytosolic protein complexes that respond to diverse danger signals by activating caspase-1. The sensor components of the inflammasome, often proteins of the nucleotide-binding oligom... | |
| Protective effects of n-6 fatty acids-enriched diet on intestinal ischaemia/reperfusion injury involve lipoxin A4 and its receptor. Br. J. Pharmacol. 172(3) , 910-23, (2015) Long-term intake of dietary fatty acids is known to predispose to chronic inflammation, but their effects on acute intestinal ischaemia/reperfusion (I/R) injury is unknown. The aim of this study was t... | |
| Vimentin filament organization and stress sensing depend on its single cysteine residue and zinc binding. Nat. Commun. 6 , 7287, (2015) The vimentin filament network plays a key role in cell architecture and signalling, as well as in epithelial-mesenchymal transition. Vimentin C328 is targeted by various oxidative modifications, but i... |
Synonyms
| (13E,15S)-15-Hydroxy-9-oxoprosta-10,13-dien-1-oic acid |
| (13E,15S)-15-Hydroxy-9-oxoprosta-10,13-dien-1-oic acid PGA1 |
| (13E,15S)-15-Hydroxy-9-oxoprosta-10,13-dien-1-oic acid,PGA1 |
| Prosta-10,13-dien-1-oic acid, 15-hydroxy-9-oxo-, (13E,15S)- |
| Prostaglandin A1 |
| MFCD00077858 |
