CAS 38965-51-4|Eriodictyol-7-O-glucoside

Introduction:Basic information about CAS 38965-51-4|Eriodictyol-7-O-glucoside, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameEriodictyol-7-O-glucoside
CAS Number38965-51-4Molecular Weight450.393
Density1.7±0.1 g/cm3Boiling Point841.0±65.0 °C at 760 mmHg
Molecular FormulaC21H22O11Melting Point171-176ºC
MSDSUSAFlash Point296.9±27.8 °C

Names

Nameeriodictyol-7-glucoside
SynonymMore Synonyms

Eriodictyol-7-O-glucoside BiologicalActivity

DescriptionEriodictyol-7-O-glucoside (Eriodictyol 7-O-β-D-glucoside), a flavonoid, is a potent free radical scavenger. Eriodictyol-7-O-glucoside is also an Nrf2 activator, confers protection against Cisplatin-induced toxicity[1].
Related CatalogSignaling Pathways >>NF-κB >>Keap1-Nrf2Research Areas >>Metabolic Disease
Target

Nrf2[1]

References

[1]. Hu Q, et, al. Eriodictyol-7-O-glucoside, a novel Nrf2 activator, confers protection against cisplatin-induced toxicity. Food Chem Toxicol. 2012 Jun;50(6):1927-32.

Chemical & Physical Properties

Density1.7±0.1 g/cm3
Boiling Point841.0±65.0 °C at 760 mmHg
Melting Point171-176ºC
Molecular FormulaC21H22O11
Molecular Weight450.393
Flash Point296.9±27.8 °C
Exact Mass450.116211
PSA186.37000
LogP0.22
Vapour Pressure0.0±3.3 mmHg at 25°C
Index of Refraction1.713
InChIKeyRAFHNDRXYHOLSH-TUYHZEGRSA-N
SMILESO=C1CC(c2ccc(O)c(O)c2)Oc2cc(OC3OC(CO)C(O)C(O)C3O)cc(O)c21
Storage condition2-8°C

Safety Information

Safety Phrases22-24/25
RIDADRNONH for all modes of transport

Articles2

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Eriodictyol-7-O-glucoside, a novel Nrf2 activator, confers protection against cisplatin-induced toxicity

Food Chem. Toxicol. 50 , 1927-1932, (2012)

Graphical abstract Eriodictyol-7-O-glucoside was identified as a novel Nrf2 activator and the present study demonstrated the efficacy of the compound in battling cisplatin-induced toxicity. [Display o...

Synonyms

3',4',5,7-Tetrahydroxyflavanone-7-glucoside
ERIODICTYOL-7-GLUCOSIDE
(2S)-2-(3,4-Dihydroxyphényl)-5-hydroxy-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyméthyl)tétrahydro-2H-pyran-2-yl]oxy}-2,3-dihydro-4H-chromén-4-one
pyracanthoside
eriodictyol-7-O-glucoside
(2S)-2-(3,4-Dihydroxyphenyl)-5-hydroxy-4-oxo-3,4-dihydro-2H-chromen-7-yl β-D-glucopyranoside
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-2,3-dihydro-5-hydroxy-, (2S)-
(2S)-2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-2,3-dihydro-4H-chromen-4-one
(2S)-2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-2,3-dihydro-4H-chromen-4-on
(2S)-2-(3,4-Dihydroxyphenyl)-5-hydroxy-4-oxo-3,4-dihydro-2H-chromen-7-yl-β-D-glucopyranoside
(S)-2-(3,4-Dihydroxyphenyl)-7-(b-D-glucopyranosyloxy)-2,3-dihydro-5-hydroxy-4H-1-benzopyran-4-one
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