CAS 1918-16-7|Propachlor
Introduction：Basic information about CAS 1918-16-7|Propachlor, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Propachlor | ||
|---|---|---|---|
| CAS Number | 1918-16-7 | Molecular Weight | 211.688 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 290.4±23.0 °C at 760 mmHg |
| Molecular Formula | C11H14ClNO | Melting Point | 67-76°C |
| MSDS | ChineseUSA | Flash Point | 129.4±22.6 °C |
| Symbol | GHS07, GHS09 | Signal Word | Warning |
Names
| Name | propachlor |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 290.4±23.0 °C at 760 mmHg |
| Melting Point | 67-76°C |
| Molecular Formula | C11H14ClNO |
| Molecular Weight | 211.688 |
| Flash Point | 129.4±22.6 °C |
| Exact Mass | 211.076385 |
| PSA | 20.31000 |
| LogP | 2.28 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.551 |
| InChIKey | MFOUDYKPLGXPGO-UHFFFAOYSA-N |
| SMILES | CC(C)N(C(=O)CCl)c1ccccc1 |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 710 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1056 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 290 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 306 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 392 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 380 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - quail
- DOSE/DURATION :
- 91 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - duck
- DOSE/DURATION :
- 512 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3458 mg/kg/26W-I
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1400 mg/kg/20D-I
- TOXIC EFFECTS :
- Liver - liver function tests impaired Blood - pigmented or nucleated red blood cells Biochemical - Metabolism (Intermediary) - other proteins
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TYPE OF TEST :
- Sperm Morphology
MUTATION DATA - TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 10 mg/kg
- REFERENCE :
- CYGEDX Cytology and Genetics (English Translation). Translation of TGANAK. (Allerton Press Inc., 150 Fifth Ave., New York, NY 10011) V.8- 1974- Volume(issue)/page/year: 14(6),38,1980 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 10 mg/kg
- REFERENCE :
- CYGEDX Cytology and Genetics (English Translation). Translation of TGANAK. (Allerton Press Inc., 150 Fifth Ave., New York, NY 10011) V.8- 1974- Volume(issue)/page/year: 14(6),38,1980 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989
Safety Information
| Symbol | GHS07, GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H317-H319-H410 |
| Precautionary Statements | P273-P280-P305 + P351 + P338-P501 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn:Harmful;N:Dangerousfortheenvironment; |
| Risk Phrases | R22;R36;R43;R50/53 |
| Safety Phrases | S24-S37-S60-S61 |
| RIDADR | UN 2811 |
| RTECS | AE1575000 |
| HS Code | 2924299014 |
Customs
| HS Code | 2924299014 |
|---|---|
| Summary | 2924299014 2-chloro-n-isopropyl-n-phenylacetamide。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0% |
Articles25
More Articles| Glutathione-dependent cytotoxicity of the chloroacetanilide herbicides alachlor, metolachlor, and propachlor in rat and human hepatoma-derived cultured cells. Cell Biol. Toxicol. 15(5) , 325-32, (1999) Alachlor, metolachlor, and propachlor are widely used chloroacetanilide herbicides. Their cytotoxicity in rat (Fa32) and human (Hep G2) hepatoma-derived cells was investigated, in connection with thei... | |
| Kinetics and mechanism of propachlor reductive transformation through nucleophilic substitution by dithionite Chemosphere 85(9) , 1438-43, (2011) Highlights ► The reductive dechlorination of propachlor was efficiently achieved by dithionite. ► The transformation of propachlor initiated by dithionite follows second-order kinetics. ► Dechlorinati... | |
| Characterization of glutathione conjugates of chloroacetanilide pesticides using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry and liquid chromatography/ion trap mass spectrometry. Rapid Commun. Mass Spectrom. 21(24) , 4017-22, (2007) Glutathione S-transferases (GSTs) isolated from maize were used to catalyze the conjugation of glutathione (GSH) with chloroacetanilide herbicides, producing stable conjugates that were structurally c... |
Synonyms
| 2-Chloro-N-isopropylacetanilide |
| Satecid |
| N-isopropyl-2-chloroacetanilide |
| 2-Chloro-N-isopropyl-N-phenyl-acetamide |
| Niticid |
| N-isopropyl-N-phenyl-chloroacetamide |
| 2-Chloro-N-isopropyl-N-phenylacetamide |
| Prolex |
| Propachlore |
| 2-Chloro-N-(1-methylethyl)-N-phenylacetamide (9CI) |
| Nitacid |
| α-chloro-N-isopropylacetanilide |
| MFCD00078731 |
| EINECS 217-638-2 |
| Bexton |
| 2-chloro-N-(1-methylethyl)-N-phenylacetamide |
| 2-chloro-N-phenyl-N-(propan-2-yl)acetamide |
| n-isopropyl-a-chloroacetanilide |
| Bexton 4L |
| 2-chloro-N-phenyl-N-propan-2-ylacetamide |
| Acetamide, 2-chloro-N-(1-methylethyl)-N-phenyl- |
| Ramrod |
| Propachlor |
