CAS 149231-65-2|Ac-Tyr-Val-Ala-Asp-AMC
| Common Name | Ac-Tyr-Val-Ala-Asp-AMC | ||
|---|---|---|---|
| CAS Number | 149231-65-2 | Molecular Weight | 665.690 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 1127.3±65.0 °C at 760 mmHg |
| Molecular Formula | C33H39N5O10 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 635.6±34.3 °C |
Names
| Name | 3-[2-[[2-[[2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]propanoylamino]-4-[(4-methyl-2-oxochromen-7-yl)amino]-4-oxobutanoic acid |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 1127.3±65.0 °C at 760 mmHg |
| Molecular Formula | C33H39N5O10 |
| Molecular Weight | 665.690 |
| Flash Point | 635.6±34.3 °C |
| Exact Mass | 665.269714 |
| PSA | 233.24000 |
| LogP | 2.58 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.605 |
| InChIKey | YGLOALWHJIANIH-PQTMRPCPSA-N |
| SMILES | CC(=O)NC(Cc1ccc(O)cc1)C(=O)NC(C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)Nc1ccc2c(C)cc(=O)oc2c1)C(C)C |
| Storage condition | −20°C |
| Water Solubility | DMSO: 10 mM The solution is stable in the dark at −20 °C for more than 1 month if no water is present. |
Safety Information
| RIDADR | NONH for all modes of transport |
|---|---|
| WGK Germany | 3 |
Articles5
More Articles| A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. Nature 356 , 768, (1992) Interleukin-1 beta (IL-1 beta)-converting enzyme cleaves the IL-1 beta precursor to mature IL-1 beta, an important mediator of inflammation. The identification of the enzyme as a unique cysteine prote... | |
| Processing/activation of CPP32-like proteases is involved in transforming growth factor beta1-induced apoptosis in rat hepatocytes. Hepatology 25 , 1516, (1997) Apoptosis induced in rat hepatocytes by transforming growth factor beta1 (TGF-beta1) was accompanied by the activation of interleukin-1beta converting enzyme (ICE)-like proteases. Cell lysates were is... | |
| Partial purification and characterization of two distinct types of caspases from human epidermis. J. Invest. Dermatol. 111 , 367-372, (1998) Recent observations demonstrated that interleukin-1beta converting enzyme family proteases, now referred to as caspase family, play central roles in apoptosis, or programmed cell death. In this study,... |
Synonyms
| acetyl-YVAD-aminomethyl coumarine |
| Ac-Tyr-Val-Ala-Asp-7-Amino-4-Methylcoumarin |
| N-Acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-α-asparagine |
| Acetyl-YVAD-AMC |
| N-Acetyl-Tyr-Val-Ala-Asp-7-amido-4-methylcoumarin |
| L-α-Asparagine, N-acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- |
| MFCD00171369 |
| Ac-Tyr-Val-Ala-Asp-MCA |
| Ac-YVAD-AMC |
| Ac-Tyr-Val-Ala-Asp-AMC |
| AMC120 |
| AC-YVAD-AMC |
| AC-TYR-VAL-ALA-ASP-AMC |
