CAS 531-53-3|Azure A chloride

Introduction:Basic information about CAS 531-53-3|Azure A chloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameAzure A chloride
CAS Number531-53-3Molecular Weight291.80
Density/Boiling Point442.8ºC at 760 mmHg
Molecular FormulaC14H14ClN3SMelting Point290 °C (dec.)(lit.)
MSDSChineseUSAFlash Point221.6ºC

Names

Nameazure A
SynonymMore Synonyms

Azure A chloride BiologicalActivity

DescriptionAzure A (chloride) is a phenothiazine dye. Azure A (chlorine) is formed by oxidation of methylene blue and has strong metachromatic. Azure A (chlorine) can be used for the study of stains and redox media for electrochemical biosensing[1][2].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
References

[1]. Snehalatha M, et al. Azure A chloride: computational and spectroscopic study[J]. Journal of Raman Spectroscopy: An International Journal for Original Work in all Aspects of Raman Spectroscopy, Including Higher Order Processes, and also Brillouin and Rayleigh Scattering, 2009, 40(2): 176-182.

[2]. Shahab S, et al. Photochromic properties of the molecule Azure A chloride in polyvinyl alcohol matrix[J]. Journal of Molecular Structure, 2015, 1101: 109-115.

Chemical & Physical Properties

Boiling Point442.8ºC at 760 mmHg
Melting Point290 °C (dec.)(lit.)
Molecular FormulaC14H14ClN3S
Molecular Weight291.80
Flash Point221.6ºC
Exact Mass291.059692
PSA70.16000
StabilityStable. Incompatible with strong oxidizing agents.

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SP5660000
CHEMICAL NAME :
Phenothiazin-5-ium, 3-amino-7-(dimethylamino)-, chloride
CAS REGISTRY NUMBER :
531-53-3
LAST UPDATED :
199709
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C14-H14-N3-S.Cl
MOLECULAR WEIGHT :
291.82
WISWESSER LINE NOTATION :
T C666 BN ISJ FZ MN1&1 &G &12/25

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
37720 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation Lungs, Thorax, or Respiration - other changes
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
59040 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation Lungs, Thorax, or Respiration - other changes
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
19340 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation Lungs, Thorax, or Respiration - other changes

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
20 umol/L/5H (Continuous)
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 1,27,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3031 No. of Facilities: 451 (estimated) No. of Industries: 4 No. of Occupations: 3 No. of Employees: 2020 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3031 No. of Facilities: 661 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 5132 (estimated) No. of Female Employees: 2765 (estimated)

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard CodesXi
Safety PhrasesS22-S24/25
RIDADRNONH for all modes of transport
WGK Germany3
RTECSSP5660000
HS Code2934300000

Customs

HS Code2934300000
Summary2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Synonyms

EINECS 208-510-7
7-(Dimethylamino)-3-imino-3H-phenothiazine Hydrochloride
Methyleneazure
7-Amino-N,N-dimethyl-3H-phenothiazin-3-iminium chloride
N,N,N'-Trimethylthionin
AZURE A, CERTIFIED, PURE
Azure AC.I. 52005
Methanaminium, N-(7-amino-3H-phenothiazin-3-ylidene)-N-methyl-, chloride (1:1)
MFCD00012112
Azure A chloride
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