CAS 53874-66-1|1-(Chloromethyl)-3-phenoxybenzene

Introduction：Basic information about CAS 53874-66-1|1-(Chloromethyl)-3-phenoxybenzene, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles1
7. Synonyms

Common Name	1-(Chloromethyl)-3-phenoxybenzene
CAS Number	53874-66-1	Molecular Weight	218.67900
Density	1.189 g/mL at 25 °C(lit.)	Boiling Point	141-142 °C(lit.)
Molecular Formula	C₁₃H₁₁ClO	Melting Point	/
MSDS	Chinese	Flash Point	>230 °F
Symbol	GHS05, GHS07	Signal Word	Danger

Names

Name	3-phenoxybenzyl chloride
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.189 g/mL at 25 °C(lit.)
Boiling Point	141-142 °C(lit.)
Molecular Formula	C₁₃H₁₁ClO
Molecular Weight	218.67900
Flash Point	>230 °F
Exact Mass	218.05000
PSA	9.23000
LogP	4.21770
Index of Refraction	n20/D 1.5900(lit.)
InChIKey	QUYVTGFWFHQVRO-UHFFFAOYSA-N
SMILES	ClCc1cccc(Oc2ccccc2)c1
Storage condition	Refrigerator (+4°C)

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CZ0790000

CHEMICAL NAME :: Benzene, 1-(chloromethyl)-3-phenoxy-

CAS REGISTRY NUMBER :: 53874-66-1

LAST UPDATED :: 199703

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C13-H11-Cl-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1224 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 56(2),16,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5723 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 55(7),93,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1666 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 56(2),16,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 1250 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - other changes

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 55(7),93,1990 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4500 mg/kg/30D-I

TOXIC EFFECTS :: Liver - other changes Blood - leukopenia Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 56(2),16,1991

Safety Information

Symbol	GHS05, GHS07
Signal Word	Danger
Hazard Statements	H302-H314
Precautionary Statements	P280-P305 + P351 + P338-P310
Personal Protective Equipment	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	C:Corrosive;
Risk Phrases	R23;R24
Safety Phrases	S26-S27-S28-S45
RIDADR	UN 1760 8/PG 3
WGK Germany	3
RTECS	CZ0790000
Packaging Group	III
Hazard Class	8
HS Code	2909309090

Customs

HS Code	2909309090
Summary	2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles1

[Experimental substantiation of MPEL of 3-phenoxybenzyl chloride in water reservoirs].

Gig. Sanit. (2) , 16-9, (1991)

On the basis of experimental studies it was established, that the threshold concentration of 3-phenoxybenzyl chloride (PBC) according to the influence on organoleptic water properties (odour) is 0.03 ...

Synonyms

3-Phenoxybenzyl chloride

3-Phenoxy-1-chloromethylbenzene

3-phenoxyphenylmethyl chloride

EINECS 258-831-1

1-(Chloromethyl)-3-phenoxybenzene

MFCD00040866

3-phenyloxyphenylmethyl chloride

m-Phenoxybenzyl chloride

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