CAS 54-30-8|Camylofine

Introduction：Basic information about CAS 54-30-8|Camylofine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Camylofine BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Customs
7. Articles3
8. Synonyms

Common Name	Camylofine
CAS Number	54-30-8	Molecular Weight	320.47000
Density	0.987g/cm3	Boiling Point	408.4ºC at 760mmHg
Molecular Formula	C₁₉H₃₂N₂O₂	Melting Point	25°C
MSDS	ChineseUSA	Flash Point	200.8ºC
Symbol	GHS07	Signal Word	Warning

Names

Name	3-methylbutyl 2-[2-(diethylamino)ethylamino]-2-phenylacetate
Synonym	More Synonyms

Camylofine BiologicalActivity

Description	Camylofin is an antimuscarinic, is a smooth muscle relaxant
Related Catalog	Signaling Pathways >>GPCR/G Protein >>mAChRSignaling Pathways >>Neuronal Signaling >>mAChRResearch Areas >>Neurological Disease

Chemical & Physical Properties

Density	0.987g/cm3
Boiling Point	408.4ºC at 760mmHg
Melting Point	25°C
Molecular Formula	C₁₉H₃₂N₂O₂
Molecular Weight	320.47000
Flash Point	200.8ºC
Exact Mass	320.24600
PSA	41.57000
LogP	3.63930
Index of Refraction	1.502
InChIKey	RYOOHIUJEJZCFT-UHFFFAOYSA-N
SMILES	CCN(CC)CCNC(C(=O)OCCC(C)C)c1ccccc1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MB9625000

CHEMICAL NAME :: Glycine, N-(2-(diethylamino)ethyl)-2-phenyl-, isopentyl ester

CAS REGISTRY NUMBER :: 54-30-8

BEILSTEIN REFERENCE NO. :: 2816984

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C19-H32-N2-O2

MOLECULAR WEIGHT :: 320.53

WISWESSER LINE NOTATION :: 2N2&2MYR&VO2Y1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 760 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DMWOAX Deutsche Medizinische Wochenschrift. (Stuttgart, Fed. Rep. Ger.) V.1-104, 1875-1979. Volume(issue)/page/year: 76,479,1951

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 175 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 76,1175,1956

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 610 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 59,113,1963

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn
Risk Phrases	22
Safety Phrases	36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	MB9625000
HS Code	2922499990

Customs

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles3

Determination of the analgesic components of Spasmomigraine tablet by liquid chromatography with ultraviolet detection.

J. AOAC Int. 90(1) , 94-101, (2007)

A procedure was developed for the determination of the analgesic components of Spasmomigraine tablets, which are ergotamine (I), propyphenazone (II), caffeine (III), camylofin (IV), and mecloxamine (V...

Use of anafortan intravenous injection for treatment of colicky pain.

J. Indian Med. Assoc. 98(8) , 479, 482, (2000)

Development and characterization of colon specific drug delivery system bearing 5-ASA and Camylofine dihydrochloride for the treatment of ulcerative colitis.

J. Drug Target. 18(8) , 589-601, (2010)

The treatment of ulcerative colitis (inflammatory bowel disease, IBD) has been achieved by using colon specific drug delivery system bearing 5-ASA and Camylofine dihydrochloride. Chitosan microspheres...

Synonyms

Adopon

Camylofine

Sintespasmil

Acamylophenine

Spasmocan

Novospasmin

Camylopin

Navadyl

Belosin

Camylofin

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