Introduction：Basic information about CAS 7057-33-2|3'-Deoxycytidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 3'-Deoxycytidine |
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| CAS Number | 7057-33-2 | Molecular Weight | 227.22 |
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| Density | 1.7±0.1 g/cm3 | Boiling Point | 497.6±55.0 °C at 760 mmHg |
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| Molecular Formula | C9H13N3O4 | Melting Point | / |
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| MSDS | / | Flash Point | 254.8±31.5 °C |
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Names
| Name | 3'-deoxycytidine |
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| Synonym | More Synonyms |
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3'-Deoxycytidine BiologicalActivity
| Description | 4-Amino-1-((2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one (3'-Deoxycytidine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Others |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
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| Boiling Point | 497.6±55.0 °C at 760 mmHg |
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| Molecular Formula | C9H13N3O4 |
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| Molecular Weight | 227.22 |
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| Flash Point | 254.8±31.5 °C |
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| Exact Mass | 227.090607 |
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| PSA | 110.60000 |
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| LogP | -1.70 |
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| Vapour Pressure | 0.0±2.9 mmHg at 25°C |
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| Index of Refraction | 1.720 |
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| InChIKey | ZHHOTKZTEUZTHX-SHYZEUOFSA-N |
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| SMILES | Nc1ccn(C2OC(CO)CC2O)c(=O)n1 |
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| Storage condition | 2-8°C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- HA3830000
- CHEMICAL NAME :
- Cytidine, 3'-deoxy-
- CAS REGISTRY NUMBER :
- 7057-33-2
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C9-H13-N3-O4
- MOLECULAR WEIGHT :
- 227.25
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA - TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - mouse Fibroblast
- DOSE/DURATION :
- 1 mg/L
- REFERENCE :
- CBRPDS Cell Biology International Reports. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 2,279,1978
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Safety Information
Synonyms
| 4-Amino-1-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-2(1H)-pyrimidinone |
| 4-Amino-1-(3-deoxy-β-D-erythro-pentofuranosyl)pyrimidin-2(1H)-on |
| 3'-deoxy-cytidine |
| 3'-Deoxycytidine |
| 3'-deoxyribicytidine |
| 3'-Deoxy-D-cytidine |
| 3'-deoxycytidine free base |
| Cytidine, 3'-deoxy- |
