Introduction：Basic information about CAS 19504-77-9|2-Pyrrolidinone,1-[(2E,4E,6E,8R)-8-hydroxy-6-methyl-1-oxo-2,4,6-dodecatrien-1-, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-Pyrrolidinone,1-[(2E,4E,6E,8R)-8-hydroxy-6-methyl-1-oxo-2,4,6-dodecatrien-1-yl]- |
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| CAS Number | 19504-77-9 | Molecular Weight | 291.39 |
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| Density | 1.088g/cm3 | Boiling Point | 481.2ºC at 760mmHg |
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| Molecular Formula | C17H25NO3 | Melting Point | / |
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| MSDS | / | Flash Point | 244.8ºC |
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Names
| Name | 1-[(2E,4E,6E,8R)-8-hydroxy-6-methyldodeca-2,4,6-trienoyl]pyrrolidin-2-one |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | Variotin is an Anti-Fungal Agent. Variotin has a strong antibiotic activity on dermatophytes such as Trichophyton, Microsporum, and Epidermophyton, and also pathogenic fungi in internal mycosis such as Blastomyces and Cryptococcus[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Fungal |
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| References | [1]. MATSUDA A, et al. Studies on antifungal activity of variotin. J Antibiot (Tokyo). 1959 Sep;12:203-9. |
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Chemical & Physical Properties
| Density | 1.088g/cm3 |
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| Boiling Point | 481.2ºC at 760mmHg |
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| Molecular Formula | C17H25NO3 |
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| Molecular Weight | 291.39 |
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| Flash Point | 244.8ºC |
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| Exact Mass | 291.18300 |
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| PSA | 57.61000 |
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| LogP | 2.68310 |
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| Vapour Pressure | 2.79E-11mmHg at 25°C |
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| Index of Refraction | 1.538 |
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| InChIKey | ZYPGADGCNXOUJP-CXVPHVKISA-N |
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| SMILES | CCCCC(O)C=C(C)C=CC=CC(=O)N1CCCC1=O |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- UY5777000
- CHEMICAL NAME :
- 2-Pyrrolidinone, 1-(8-hydroxy-6-methyl-2,4,6-dodecatrienoyl)-, (E,E,E)-(R)-
- CAS REGISTRY NUMBER :
- 19504-77-9
- LAST UPDATED :
- 198104
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C17-H25-N-O3
- MOLECULAR WEIGHT :
- 291.43
- WISWESSER LINE NOTATION :
- T5NVTJ AV1U2U1Y1&U1YQ4
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 320 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978 Volume(issue)/page/year: 3,2004,1978
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Synonyms
| Leofungine |
| Supral |
| EINECS 243-116-9 |
| Pecilocin |
| variotin |
