CAS 20826-04-4|5-Bromonicotinic acid
Introduction：Basic information about CAS 20826-04-4|5-Bromonicotinic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5-Bromonicotinic acid | ||
|---|---|---|---|
| CAS Number | 20826-04-4 | Molecular Weight | 202.01 |
| Density | 1.8±0.1 g/cm3 | Boiling Point | 328.5±27.0 °C at 760 mmHg |
| Molecular Formula | C6H4BrNO2 | Melting Point | 178-180 °C(lit.) |
| MSDS | USA | Flash Point | 152.5±23.7 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 5-bromopyridine-3-carboxylic acid |
|---|---|
| Synonym | More Synonyms |
5-Bromonicotinic acid BiologicalActivity
| Description | 5-Bromonicotinic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
Chemical & Physical Properties
| Density | 1.8±0.1 g/cm3 |
|---|---|
| Boiling Point | 328.5±27.0 °C at 760 mmHg |
| Melting Point | 178-180 °C(lit.) |
| Molecular Formula | C6H4BrNO2 |
| Molecular Weight | 202.01 |
| Flash Point | 152.5±23.7 °C |
| Exact Mass | 200.942535 |
| PSA | 50.19000 |
| LogP | 1.22 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.617 |
| InChIKey | FQIUCPGDKPXSLL-UHFFFAOYSA-N |
| SMILES | O=C(O)c1cncc(Br)c1 |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 462 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - ptosis Behavioral - somnolence (general depressed activity) Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- JOPHDQ Journal of Pharmacobio-Dynamics. (Japan Pub. Trading Co. (USA), 1255 Howard St., San Francisco, CA 94103) V.1- 1978- Volume(issue)/page/year: 10,35,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 20,29,1986
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | QT0868000 |
| HS Code | 2933399090 |
Preparation
Customs
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles4
More Articles| Agonist lead identification for the high affinity niacin receptor GPR109a. Bioorg. Med. Chem. Lett. 17 , 4914-9, (2007) A strategy for lead identification of new agonists of GPR109a, starting from known compounds shown to activate the receptor, is described. Early compound triage led to the formulation of a binding hyp... | |
| Iodopyridine-for-iodobenzene substitution for use with low molecular weight radiopharmaceuticals: application to m-iodobenzylguanidine. Bioconjug. Chem. 9(6) , 758-64, (1998) Substituting a pyridine ring for a benzene ring in the acylation agent N-succinimidyl 3-iodobenzoate has resulted in a useful approach for the radiohalogenation of monoclonal antibodies, peptides, and... | |
| Drug-protein conjugates: haptenation of 1-methyl-10 alpha-methoxydihydrolysergol and 5-bromonicotinic acid to albumin for the production of epitope-specific monoclonal antibodies against nicergoline. J. Pharm. Sci. 84(9) , 1120-5, (1995) Two types of monoclonal antibodies were used for the determination of nicergoline in biological matrices. The antibodies were prepared with the hydrolysis products 5-bromonicotinic acid and 1-methyl-1... |
Synonyms
| Nicotinic acid,5-bromo |
| 5-Bromonicotinic acid |
| 5-Bromo-3-pyridinecarboxylic Acid |
| 5-Bromopyridine-3-carboxylic acid,5-Bromonicotinic acid |
| 3-Pyridinecarboxylic acid,5-bromo |
| 3-bromo-5-pyridine-carboxylic acid |
| 5-bromonictotinic acid |
| 3-Bromo pyridine-5-carboxylic acid |
| 5-bromonicotininc acid |
| 3-Pyridinecarboxylic acid, 5-bromo- |
| 5-Bromopyridine-3-carboxylic acid |
| EINECS 244-065-5 |
| MFCD00009783 |
| 5-Bromo Nicotinic Acid |
