CAS 2664-63-3|4,4′-Thiodiphenol

Introduction：Basic information about CAS 2664-63-3|4,4′-Thiodiphenol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles2
7. Synonyms

Common Name	4,4′-Thiodiphenol
CAS Number	2664-63-3	Molecular Weight	218.272
Density	1.4±0.1 g/cm3	Boiling Point	452.7±30.0 °C at 760 mmHg
Molecular Formula	C₁₂H₁₀O₂S	Melting Point	154-156 °C(lit.)
MSDS	ChineseUSA	Flash Point	219.7±23.3 °C
Symbol	GHS05	Signal Word	Danger

Names

Name	4,4'-thiodiphenol
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	452.7±30.0 °C at 760 mmHg
Melting Point	154-156 °C(lit.)
Molecular Formula	C₁₂H₁₀O₂S
Molecular Weight	218.272
Flash Point	219.7±23.3 °C
Exact Mass	218.040146
PSA	65.76000
LogP	3.34
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.717
InChIKey	VWGKEVWFBOUAND-UHFFFAOYSA-N
SMILES	Oc1ccc(Sc2ccc(O)cc2)cc1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SN0800000

CHEMICAL NAME :: Phenol, 4,4'-thiodi-

CAS REGISTRY NUMBER :: 2664-63-3

LAST UPDATED :: 199710

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C12-H10-O2-S

MOLECULAR WEIGHT :: 218.28

WISWESSER LINE NOTATION :: QR DSR DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810 Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year: A408,1971

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810 Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year: A408,1971 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3362 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810 Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year: A408,1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 13,154,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >10250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810 Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year: A408,1971 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 3 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0044 No. of Facilities: 69 (estimated) No. of Industries: 3 No. of Occupations: 3 No. of Employees: 1146 (estimated)

Safety Information

Symbol	GHS05
Signal Word	Danger
Hazard Statements	H314
Precautionary Statements	P280-P305 + P351 + P338-P310
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	C:Corrosive;
Risk Phrases	R34
Safety Phrases	S26-S27-S36/37/39-S45
RIDADR	UN 3261 8/PG 2
WGK Germany	2
RTECS	SN0800000
Packaging Group	II
Hazard Class	8
HS Code	29309070

Customs

HS Code	29309070

Articles2

Screening of bisphenol A, triclosan and paraben analogues as modulators of the glucocorticoid and androgen receptor activities.

Toxicol. In Vitro 29(1) , 8-15, (2014)

A homeostasis of the glucocorticoid and androgen endocrine system is essential to human health. Their disturbance can lead to various diseases, for example cardiovascular, inflammatory and autoimmune ...

[Materials for the establishment of maximum allowable concentrations of bis (4-oxyphenyl) sulfide in the working zone air].

Gig. Tr. Prof. Zabol. (1) , 31-2, (1991)

Synonyms

Bis(4-hydroxyphenyl) sulfide

Thiobisphenol

4,4'-Thiobisphenol

MFCD00002349

Phenol, 4,4'-thiobis-

4-(4-hydroxyphenyl)sulfanylphenol

4-hydroxyphenyl sulphide

p,p'-Dihydroxydiphenyl sulfide

4,4′-Thiodiphenol

4,4'-thiodiphenol

4,4'-Thiobis-phenol

4,4'-dihydroxyldiphenyl sulfide

4,4'-Sulfanediyldiphenol

4,4'-Dihydroxydiphenyl sulfide

4,4-Thiodiphenol

EINECS 220-197-9

Phenol,4,4'-thiobis

4,4'-Dihydroxy diphenyl sulfide

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