CAS 59887-89-7|7-Hydroxy-4H-chromen-4-one

Introduction:Basic information about CAS 59887-89-7|7-Hydroxy-4H-chromen-4-one, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name7-Hydroxy-4H-chromen-4-one
CAS Number59887-89-7Molecular Weight162.14200
Density1.403g/cm3Boiling Point345.4ºC at 760 mmHg
Molecular FormulaC9H6O3Melting Point215-220ºC
MSDS/Flash Point148.1ºC

Names

Name7-hydroxychromen-4-one
SynonymMore Synonyms

7-Hydroxy-4H-chromen-4-one BiologicalActivity

Description7-Hydroxychromone is a Src kinase inhibitor with an IC50 of <300 μM.
Related CatalogSignaling Pathways >>Protein Tyrosine Kinase/RTK >>SrcNatural Products >>FlavonoidsResearch Areas >>Cancer
Target

IC50: <300 μM (Src)[1]

In Vitro7-Hydroxychromone (compound 8) is a 4-oxo-4H-1-benzopyran derivative which can inhibit Src kinase with an IC50 of <300 μM[1].
References

[1]. Karam Chand, et al. Synthesis, Antiproliferative, and c-Src Kinase Inhibitory Activities of 4-Oxo-4H-1-benzopyran Derivatives. ‎J. Heterocycl. Chem. 2014.

Chemical & Physical Properties

Density1.403g/cm3
Boiling Point345.4ºC at 760 mmHg
Melting Point215-220ºC
Molecular FormulaC9H6O3
Molecular Weight162.14200
Flash Point148.1ºC
Exact Mass162.03200
PSA50.44000
LogP1.49860
Index of Refraction1.64
Storage condition-20℃

Safety Information

Hazard CodesXn
Risk Phrases22
HS Code2932999099

Customs

HS Code2932999099
Summary2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

7-Hydroxybenzopyran-4-one
7-oxidanylchromen-4-one
7-Hydroxy-4-benzopyrone
7-hydroxy-4H-4-chromenone
7-hydroxy-chromen-4-one
7-Hydroxychromone
7-hydroxy-4H-chromen-4-one
7-hydroxy-4-chromone
EINECS 261-973-7
CAS 54893-54-8|6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline
CAS 599194-06-6|Benzenamine, 2-[2-(1-methylethyl)cyclopropyl]- (9CI)
Recommended......
TOP