Introduction：Basic information about CAS 73981-34-7|Kamebakaurine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Kamebakaurine |
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| CAS Number | 73981-34-7 | Molecular Weight | 350.44900 |
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| Density | 1.3g/cm3 | Boiling Point | 563.5ºC at 760 mmHg |
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| Molecular Formula | C20H30O5 | Melting Point | 7ºC |
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| MSDS | / | Flash Point | 308.6ºC |
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Names
| Name | kamebakaurin |
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| Synonym | More Synonyms |
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Kamebakaurine BiologicalActivity
| Description | Kamebakaurin is a natural compound isolated from Isodon japonicus. Kamebakaurin is a potent inhibitor of NF-κB activation by directly targeting DNA-binding activity of p50[1]. |
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| Related Catalog | Research Areas >>CancerResearch Areas >>Inflammation/Immunology |
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| References | [1]. Lee JH, et al. Kaurane diterpene, kamebakaurin, inhibits NF-kappa B by directly targeting the DNA-binding activity of p50 and blocks the expression of antiapoptotic NF-kappa B target genes. J Biol Chem. 2002 May 24;277(21):18411-20. |
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Chemical & Physical Properties
| Density | 1.3g/cm3 |
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| Boiling Point | 563.5ºC at 760 mmHg |
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| Melting Point | 7ºC |
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| Molecular Formula | C20H30O5 |
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| Molecular Weight | 350.44900 |
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| Flash Point | 308.6ºC |
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| Exact Mass | 350.20900 |
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| PSA | 97.99000 |
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| LogP | 1.03920 |
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| Index of Refraction | 1.601 |
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| InChIKey | WHSUEVLJUHPROF-BIGDWJEQSA-N |
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| SMILES | C=C1C(=O)C23C(O)CC4C(C)(C)CCC(O)C4(CO)C2CCC1C3O |
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Synonyms
| 1,7,14,20-Tetrahydroxykaur-16-en-15-one (1alpha,7alpha,14R) |
| Kaur-16-en-15-one,1,7,14,20-tetrahydroxy-,(1alpha,7alpha,14R) |
