CAS 673-22-3|2-Hydroxy-4-methoxybenzaldehyde

Introduction：Basic information about CAS 673-22-3|2-Hydroxy-4-methoxybenzaldehyde, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 2-Hydroxy-4-methoxybenzaldehyde BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
5. Safety Information
6. Customs
7. Articles15
8. Synonyms

Common Name	2-Hydroxy-4-methoxybenzaldehyde
CAS Number	673-22-3	Molecular Weight	152.15
Density	1.2±0.1 g/cm3	Boiling Point	271.5±20.0 °C at 760 mmHg
Molecular Formula	C₈H₈O₃	Melting Point	41-43 °C(lit.)
MSDS	ChineseUSA	Flash Point	112.1±15.3 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	2-Hydroxy-4-methoxybenzaldehyde
Synonym	More Synonyms

2-Hydroxy-4-methoxybenzaldehyde BiologicalActivity

Description	2-Hydroxy-4-methoxybenzaldehyde, a chemical compound and an isomer of Vanillin, could be used to synthesis Urolithin M7[1]. 2-hydroxy-4-methoxybenzaldehyde is a potent tyrosinase inhibitor from three East African medicinal plants, Mondia whitei, Rhus vulgaris Meikle, and Sclerocarya caffra Sond[2].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Metabolic Enzyme/Protease >>Tyrosinase
Target	Tyrosinase[2].
References	[1]. Bodwell Graham, et al. An Inverse Electron-Demand Diels-Alder-Based Total Synthesis of Urolithin M7. Synlett. 2011 (15): 2245. [2]. Kubo I, et al. 2-Hydroxy-4-methoxybenzaldehyde: a potent tyrosinase inhibitor from African medicinal plants. Planta Med. 1999 Feb;65(1):19-22.

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	271.5±20.0 °C at 760 mmHg
Melting Point	41-43 °C(lit.)
Molecular Formula	C₈H₈O₃
Molecular Weight	152.15
Flash Point	112.1±15.3 °C
Exact Mass	152.047348
PSA	46.53000
LogP	1.79
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.588
InChIKey	WZUODJNEIXSNEU-UHFFFAOYSA-N
SMILES	COc1ccc(C=O)c(O)c1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BZ2810000

CHEMICAL NAME :: p-Anisaldehyde, 2-hydroxy-

CAS REGISTRY NUMBER :: 673-22-3

BEILSTEIN REFERENCE NO. :: 1072443

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C8-H8-O3

MOLECULAR WEIGHT :: 152.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 500 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 206,17,1988

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant
Risk Phrases	R36/37/38
Safety Phrases	S26-S36-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	BZ2810000
HS Code	29124900

Customs

HS Code	2912499000
Summary	2912499000. other aldehyde-ethers, aldehyde-phenols and aldehydes with other oxygen function. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles15

3D-QSAR and molecular docking studies of benzaldehyde thiosemicarbazone, benzaldehyde, benzoic acid, and their derivatives as phenoloxidase inhibitors.

Bioorg. Med. Chem. 15 , 2006-15, (2007)

Phenoloxidase (PO), also known as tyrosinase, is a key enzyme in insect development, responsible for catalyzing the hydroxylation of tyrosine into o-diphenols and the oxidation of o-diphenols into o-q...

Flavoring extracts of Hemidesmus indicus roots and Vanilla planifolia pods exhibit in vitro acetylcholinesterase inhibitory activities.

Plant Foods Hum. Nutr. 68(3) , 247-53, (2013)

Acetylcholinesterase inhibitors (AChEIs) are important for treatment of Alzheimer's disease and other neurological disorders. Search for potent and safe AChEIs from plant sources still continues. In t...

Inhibition of Cancer Cell Proliferation and Antiradical Effects of Decoction, Hydroalcoholic Extract, and Principal Constituents of Hemidesmus indicus R. Br.

Phytother Res. 29 , 857-63, (2015)

Indian Sarsaparilla (Hemidesmus indicus R. Br.) is widely used in Indian traditional medicine. In the present work, we explored the effects of decoction, traditional Ayurvedic preparation, and hydroal...

Synonyms

o-Hydroxy-p-methoxybenzaldehyde

VHR BQ DO1

2-HO-4-MeO-C6H3CHO

2-Hydroxy-4-methoxybenzaldehyde

4-Methoxysalicylaldehyde

4-Methoxysalicyaldehyde

Salicylaldehyde, 4-methoxy-

Benzaldehyde,2-hydroxy-4-methoxy

2-Hydroxy-p-anisaldehyde

Benzaldehyde, 2-hydroxy-4-methoxy-

p-Anisaldehyde,2-hydroxy

2-hydroxy-4-methoxy benzaldehyde

4-methoxy-salicylaldehyde

Salicylaldehyde,4-methoxy

EINECS 211-604-0

4-methoxy-2-hydroxybenzaldehyde

MFCD00003327

p-Anisaldehyde, 2-hydroxy-

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