CAS 53780-34-0|Mefluidide

Introduction:Basic information about CAS 53780-34-0|Mefluidide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameMefluidide
CAS Number53780-34-0Molecular Weight310.29
Density1.464g/cm3Boiling Point/
Molecular FormulaC11H13F3N2O3SMelting Point183-185°
MSDSChineseUSAFlash Point/

Names

Namemefluidide
SynonymMore Synonyms

Mefluidide BiologicalActivity

DescriptionMefluidide is a potent inhibitor of KCS6, CER60 and CER1 enzymes and can be used in herbicide research[1].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
References

[1]. Tresch S, et al. Inhibition of saturated very-long-chain fatty acid biosynthesis by mefluidide and perfluidone, selective inhibitors of 3-ketoacyl-CoA synthases. Phytochemistry. 2012 Apr;76:162-71.  

Chemical & Physical Properties

Density1.464g/cm3
Melting Point183-185°
Molecular FormulaC11H13F3N2O3S
Molecular Weight310.29
Exact Mass310.06000
PSA83.65000
LogP3.75010
Index of Refraction1.539
InChIKeyOKIBNKKYNPBDRS-UHFFFAOYSA-N
SMILESCC(=O)Nc1cc(NS(=O)(=O)C(F)(F)F)c(C)cc1C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AE2460000
CHEMICAL NAME :
Acetanilide, 2',4'-dimethyl-5-((trifluoromethyl)sulfonamido)-
CAS REGISTRY NUMBER :
53780-34-0
LAST UPDATED :
199612
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C11-H13-F3-N2-O3-S
MOLECULAR WEIGHT :
310.32
WISWESSER LINE NOTATION :
FXFFSWMR B1 D1 EMV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85ARAE "Agricultural Chemicals," Thomson, W.T., 4 vols., Fresno, CA, Thomson Publications, 1976/77 revision Volume(issue)/page/year: 3,66,1976/1977
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>8500 mg/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A256,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1920 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,545,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A256,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
>4620 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A256,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - duck
DOSE/DURATION :
>4640 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,545,1991 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

Safety Information

RIDADRUN3077 (solid); UN3082 (liquid)
RTECSAE2460000
HS Code2935009015

Customs

HS Code2935009015
Summary2935009015 n-(2,4-dimethyl-5-(trifluoromethylsulfonamido)phenyl)acetamide。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:35.0%

Articles6

More Articles
Inhibition of saturated very-long-chain fatty acid biosynthesis by mefluidide and perfluidone, selective inhibitors of 3-ketoacyl-CoA synthases.

Phytochemistry 76 , 162-71, (2012)

The trifluoromethanesulphonanilides mefluidide and perfluidone are used in agriculture as plant growth regulators and herbicides. Despite the fact that mefluidide and perfluidone have been investigate...

Mefluidide treatment of tall fescue pastures: intake and animal performance.

J. Anim. Sci. 68(10) , 3399-405, (1990)

Twelve Hereford heifers were used in a grazing experiment to determine intake and digestibility of tall fescue forage treated with the plant growth regulator mefluidide. Additionally, steer and heifer...

Fate of the plant growth regulator mefluidide [N-[2,4-dimethyl-5-[[(trifluoromethyl)sulfonyl]amino]phenyl]acetamide] in a cow and sheep.

J. Agric. Food Chem. 28(6) , 1286-8, (1980)

Synonyms

N-[2,4-dimethyl-5-(trifluoromethylsulfonylamino)phenyl]acetamide
2',4'-dimethyl-5'-trifluoromethylsulfonylaminoacetanilide
N-[2,4-dimethyl-5-[[(trifluoromethyl)sulfonyl]amino]phenyl]acetamide
Embark
Embark plant growth regulator
5’-(1,1,1-trifluoromethanesulfonamido)acet-2’,4’-xylidide
EINECS 258-767-4
5-Acetamido-2,4-dimethyltrifluoromethanesulfonanilide
Embark 2S
N-[2,4-dimethyl-5-(1,1,1-trifluoromethanesulfonamido)phenyl]acetamide
Vistar herbicide
VEL 3973
Vistar
Trim-Cut
MEFLUIDIDE
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