Introduction：Basic information about CAS 59170-23-9|bevantolol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | bevantolol |
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| CAS Number | 59170-23-9 | Molecular Weight | 345.433 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 518.3±50.0 °C at 760 mmHg |
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| Molecular Formula | C20H27NO4 | Melting Point | / |
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| MSDS | / | Flash Point | 267.3±30.1 °C |
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Names
| Name | bevantolol |
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| Synonym | More Synonyms |
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bevantolol BiologicalActivity
| Description | Bevantolol is a selective β-1 adrenoceptor antagonist. Bevantolol can be used for the research of angina pectoris and hypertension[1]. |
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| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>GPCR/G Protein >>Adrenergic Receptor |
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| Target | Beta-1 adrenergic receptor |
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| References | [1]. Williams EMV. Bevantolol: a beta-1 adrenoceptor antagonist with unique additional actions. J Clin Pharmacol. 1987 Jul;27(7):450-60. [2]. Dukes ID, et, al. Cardiovascular effects of bevantolol, a selective beta 1-adrenoceptor antagonist with a novel pharmacological profile. Br J Pharmacol. 1985 Feb;84(2):365-80. |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 518.3±50.0 °C at 760 mmHg |
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| Molecular Formula | C20H27NO4 |
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| Molecular Weight | 345.433 |
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| Flash Point | 267.3±30.1 °C |
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| Exact Mass | 345.194000 |
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| PSA | 59.95000 |
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| LogP | 3.38 |
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| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
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| Index of Refraction | 1.551 |
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| InChIKey | HXLAFSUPPDYFEO-UHFFFAOYSA-N |
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| SMILES | COc1ccc(CCNCC(O)COc2cccc(C)c2)cc1OC |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- UB2910000
- CHEMICAL NAME :
- 2-Propanol, 1-((2-(3,4-dimethoxyphenyl)ethyl)amino)-3-(3-methylph enoxy)-
- CAS REGISTRY NUMBER :
- 59170-23-9
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C20-H27-N-O4
- MOLECULAR WEIGHT :
- 345.48
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA - TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Rodent - hamster Cells - not otherwise specified
- DOSE/DURATION :
- 250 mg/L
- REFERENCE :
- EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 17(Suppl 19),39,1991
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Safety Information
Customs
| HS Code | 2922299090 |
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| Summary | 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| (±)-1-[(3,4-Dimethoxyphenethyl)amino]-3-(m-tolyloxy)-2-propanol |
| (±)-1-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-methylphenoxy)-2-propanol |
| 2-Propanol, 1-[[2-(3,4-dimethoxyphenyl)ethyl]amino]-3-(3-methylphenoxy)- |
| Bevantolol [INN:BAN] |
| 1-[2-(3,4-dimethoxyphenyl)-ethylamino]-3-(3-methyl-phenoxy)-2-propanol |
| 1-[2-(3,4-Dimethoxyphenyl)ethylamino]-3-m-tolyloxy-propan-2-ol |
| bevantololum [INN_la] |
| 1-{[2-(3,4-Dimethoxyphenyl)ethyl]amino}-3-(3-methylphenoxy)propan-2-ol |
| 1-(3,4-Dimethoxyphenethylamino)-3-(m-tolyloxy)-2-propanol |
| Bevantololum [INN-Latin] |
| CI 775 |
| Bevantololum |
| BEVANTOLOL |
| 1-{[2-(3,4-Dimethoxyphenyl)ethyl]amino}-3-(3-methylphenoxy)-2-propanol |
| l-(3-methylphenoxy)-3-((2-(3,4-dimethoxyphenyl)-ethyl)-amino)-2-propanol |
| 1-[2-(3,4-dimethoxyphenyl)ethylamino]-3-(3-methylphenoxy)propan-2-ol |
