CAS 556-67-2|Octamethylcyclotetrasiloxane
Introduction：Basic information about CAS 556-67-2|Octamethylcyclotetrasiloxane, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Octamethylcyclotetrasiloxane | ||
|---|---|---|---|
| CAS Number | 556-67-2 | Molecular Weight | 296.616 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 175.0±0.0 °C at 760 mmHg |
| Molecular Formula | C8H24O4Si4 | Melting Point | 17-18 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 63.2±23.0 °C |
| Symbol | GHS02, GHS08 | Signal Word | Warning |
Names
| Name | octamethylcyclotetrasiloxane |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 175.0±0.0 °C at 760 mmHg |
| Melting Point | 17-18 °C(lit.) |
| Molecular Formula | C8H24O4Si4 |
| Molecular Weight | 296.616 |
| Flash Point | 63.2±23.0 °C |
| Exact Mass | 296.075165 |
| PSA | 36.92000 |
| LogP | 2.87360 |
| Vapour density | 1 (vs air) |
| Vapour Pressure | 1.6±0.3 mmHg at 25°C |
| Index of Refraction | 1.423 |
| InChIKey | HMMGMWAXVFQUOA-UHFFFAOYSA-N |
| SMILES | C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 |
| Storage condition | 2-8°C |
| Water Solubility | INSOLUBLE |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1230,1986
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1230,1986 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1540 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0538262
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 48 gm/m3/8H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0538262
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1770 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Gastrointestinal - changes in structure or function of salivary glands Liver - other changes
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0538262
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 794 uL/kg
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - hematuria
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0538262 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 300 ppm/6H/13W-I
- TOXIC EFFECTS :
- Liver - changes in liver weight
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0530406
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 697 ppm/6H/28D-I
- TOXIC EFFECTS :
- Liver - changes in liver weight
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0516677
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - hamster
- DOSE/DURATION :
- 697 ppm/6H/28D-I
- TOXIC EFFECTS :
- Liver - changes in liver weight
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0516677 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3232 No. of Facilities: 128 (estimated) No. of Industries: 8 No. of Occupations: 12 No. of Employees: 3383 (estimated) No. of Female Employees: 1689 (estimated)
Safety Information
| Symbol | GHS02, GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H226-H361-H413 |
| Precautionary Statements | P281 |
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R53;R62 |
| Safety Phrases | S36/37-S46-S51-S61 |
| RIDADR | UN 1993 3/PG 3 |
| WGK Germany | 1 |
| RTECS | GZ4397000 |
| Packaging Group | III |
| Hazard Class | 3 |
Articles29
More Articles| Siloxane treatment by adsorption into porous materials. Environ. Technol. 30(10) , 1073-83, (2009) Siloxanes are widely used in different applications: health care, dry cleaning, household products, paints and coatings, paper, personal care, for example. This explains their prevalence in the enviro... | |
| Allometric relationships to liver tissue concentrations of cyclic volatile methyl siloxanes in Atlantic cod Environ. Pollut. 190 , 109-14, (2014) Spatial distribution and relationship of allometric measurements (length, weight and age) to liver concentrations of cyclic volatile methyl siloxanes (cVMS) including octamethylcyclotetrasiloxane (D4)... | |
| [Analysis of the volatile oils chemical constituents of roots of Actinidia deliciosa]. Zhong Yao Cai 31(5) , 677-8, (2008) To analyze the volatile oils chemical constituents of roots of Actinidia deliciosa.The volatile oils fraction of roots of Actinidia deliciosa. were extracted by water vapor distilling, and then the co... |
Synonyms
| EINECS 209-136-7 |
| Cyclotetrasiloxane, 2,2,4,4,6,6,8,8-octamethyl- |
| Octamethylcyclotetrasiloxane |
| MFCD00003269 |
| 2,2,4,4,6,6,8,8-Octamethyl-1,3,5,7,2,4,6,8-tetroxatetrasilocane |
| 2,2,4,4,6,6,8,8-octamethyl-1,3,5,7,2,4,6,8-tetraoxatetrasilocane |
