Introduction：Basic information about CAS 860-22-0|Indigo carmine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Indigo carmine is an efficient reagent for the determination of ozone by chemlluminescence (CL)[1].
Related Catalog
Research Areas >>OthersSignaling Pathways >>Others >>Others
In Vitro
Indigo carmine in a 0.2% aqueous solution is blue at pH 11.4 and yellow at 13.0. Indigo carmine is also a redox indicator, turning yellow upon reduction[1].
References
[1]. K Takeuchi, et al. Quantitative Determination of Aqueous-Phase Ozone by Chemiluminescence Using indigo-5,5'-disulfonate. Anal Chem. 1989 Mar 15;61(6):619-23.
(delta(sup 2,2')-Biindoline)-5,5'-disulfonic acid, 3,3'-dioxo-, disodium salt
CAS REGISTRY NUMBER :
860-22-0
LAST UPDATED :
199709
DATA ITEMS CITED :
16
MOLECULAR FORMULA :
C16-H8-N2-O8-S2.2Na
MOLECULAR WEIGHT :
466.36
WISWESSER LINE NOTATION :
T56 BMYVJ GSWO CU- CT56 BMYVJ GSWO &-NA- 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
93 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
405 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
9 gm/kg/2Y-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
TYPE OF TEST :
Cytogenetic analysis
TYPE OF TEST :
Cytogenetic analysis
TYPE OF TEST :
Sister chromatid exchange
MUTATION DATA
TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
20 umol/L/5H (Continuous)
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 1,27,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84752 No. of Facilities: 314 (estimated) No. of Industries: 5 No. of Occupations: 6 No. of Employees: 1736 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84752 No. of Facilities: 393 (estimated) No. of Industries: 7 No. of Occupations: 28 No. of Employees: 9691 (estimated) No. of Female Employees: 3035 (estimated)
Safety Information
Symbol
GHS07
Signal Word
Warning
Hazard Statements
H302
Personal Protective Equipment
dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes
Xn:Harmful
Risk Phrases
R22
Safety Phrases
S22-S24/25
RIDADR
NONH for all modes of transport
WGK Germany
3
RTECS
DU3000000
HS Code
32041200
Customs
HS Code
2933990090
Summary
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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