CAS 95648-75-2|2'-DEOXYGUANOSINE 5'-TRIPHOSPHATE DILITHIUM SALT

Introduction：Basic information about CAS 95648-75-2|2'-DEOXYGUANOSINE 5'-TRIPHOSPHATE DILITHIUM SALT, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	2'-DEOXYGUANOSINE 5'-TRIPHOSPHATE DILITHIUM SALT
CAS Number	95648-75-2	Molecular Weight	519.04700
Density	/	Boiling Point	/
Molecular Formula	C₁₀H₁₄Li₂N₅O₁₃P₃	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	dilithium,(2R,3S,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-2-[[hydroxy-[hydroxy(phosphonooxy)phosphoryl]oxyphosphoryl]oxymethyl]oxolan-3-olate
Synonym	More Synonyms

BiologicalActivity

Description	dGTP-15N5 (2'-Deoxyguanosine-5'-triphosphate-15N5) dilithium is 15N labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
Related Catalog	Research Areas >>CancerResearch Areas >>InfectionSignaling Pathways >>Cell Cycle/DNA Damage >>DNA/RNA SynthesisSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Kapoor I, et al. Nucleoside Diphosphate Kinase Escalates A-to-C Mutations in MutT-Deficient Strains of Escherichia coli. J Bacteriol. 2019;202(1):e00567-19. Published 2019 Dec 6.

Description

dGTP-15N5 (2'-Deoxyguanosine-5'-triphosphate-15N5) dilithium is 15N labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.

Related Catalog

Research Areas >>CancerResearch Areas >>InfectionSignaling Pathways >>Cell Cycle/DNA Damage >>DNA/RNA SynthesisSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Kapoor I, et al. Nucleoside Diphosphate Kinase Escalates A-to-C Mutations in MutT-Deficient Strains of Escherichia coli. J Bacteriol. 2019;202(1):e00567-19. Published 2019 Dec 6.

Chemical & Physical Properties

Molecular Formula	C₁₀H₁₄Li₂N₅O₁₃P₃
Molecular Weight	519.04700
Exact Mass	519.01200
PSA	313.96000
LogP	0.15110
InChIKey	JMSIWULFUCIEMD-FVALZTRZSA-L
SMILES	Nc1nc2c(ncn2C2CC(O)C(COP(=O)([O-])OP(=O)([O-])OP(=O)(O)O)O2)c(=O)[nH]1.[Li+].[Li+]

Safety Information

Safety Phrases	22-24/25
WGK Germany	3

Synonyms

einecs 306-016-7

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