Introduction：Basic information about CAS 838-07-3|2'-Deoxy-5-methylcytidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2'-Deoxy-5-methylcytidine |
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| CAS Number | 838-07-3 | Molecular Weight | 241.244 |
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| Density | 1.6±0.1 g/cm3 | Boiling Point | 492.8±55.0 °C at 760 mmHg |
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| Molecular Formula | C10H15N3O4 | Melting Point | 217-219 °C(lit.) |
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| MSDS | / | Flash Point | 251.9±31.5 °C |
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Names
| Name | 5-methyl-2'-deoxycytidine |
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| Synonym | More Synonyms |
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2'-Deoxy-5-methylcytidine BiologicalActivity
| Description | 5-Methyl-2'-deoxycytidine in single-stranded DNA can act in cis to signal de novo DNA methylation[1][2]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Epigenetics >>DNA Methyltransferase |
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| Target | Human Endogenous Metabolite |
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| References | [1]. Christman JK, et al. 5-Methyl-2'-deoxycytidine in single-stranded DNA can act in cis to signal de novo DNA methylation. Proc Natl Acad Sci U S A. 1995 Aug 1;92(16):7347-51. [2]. Testillano PS, et al. The 5-methyl-deoxy-cytidine (5mdC) localization to reveal in situ the dynamics of DNA methylation chromatin pattern in a variety of plant organ and tissue cells during development. Physiol Plant. 2013 Sep;149(1):104-13. |
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Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
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| Boiling Point | 492.8±55.0 °C at 760 mmHg |
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| Melting Point | 217-219 °C(lit.) |
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| Molecular Formula | C10H15N3O4 |
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| Molecular Weight | 241.244 |
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| Flash Point | 251.9±31.5 °C |
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| Exact Mass | 241.106262 |
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| PSA | 110.60000 |
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| LogP | -1.28 |
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| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
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| Index of Refraction | 1.694 |
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| InChIKey | LUCHPKXVUGJYGU-XLPZGREQSA-N |
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| SMILES | Cc1cn(C2CC(O)C(CO)O2)c(=O)nc1N |
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| Storage condition | −20°C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- HA3860000
- CHEMICAL NAME :
- Cytidine, 2'-deoxy-5-methyl-
- CAS REGISTRY NUMBER :
- 838-07-3
- BEILSTEIN REFERENCE NO. :
- 0024189
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C10-H15-N3-O4
- MOLECULAR WEIGHT :
- 241.28
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA - TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 10 umol/L
- REFERENCE :
- BBACAQ Biochimica et Biophysica Acta. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1947- Volume(issue)/page/year: 697,286,1982
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Safety Information
| Hazard Codes | Xi |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | 26-36 |
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| WGK Germany | 3 |
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| RTECS | HA3860000 |
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| HS Code | 2934999090 |
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Customs
| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 4-Amino-1-(2-deoxy-β-D-glycero-pentofuranosyl)-5-methylpyrimidin-2(1H)-one |
| 4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-5-methylpyrimidin-2(1H)-on |
| 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidin-2-one |
| 4-Amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-5-methyl-2(1H)-pyrimidinone |
| 2'-Deoxy-5-methylcytidine |
| EINECS 212-655-1 |
| Cytidine, 2'-deoxy-5-methyl- |
| MFCD00006549 |
| 2(1H)-pyrimidinone, 4-amino-1-(2-deoxy-β-D-glycero-pentofuranosyl)-5-methyl- |
| 5-Methyl-2'-deoxy-cytidine |
| 5-Methyl-2'-deoxycytidine |
