Introduction:Basic information about CAS 70-10-0|Ticlatone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Ticlatone |
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| CAS Number | 70-10-0 | Molecular Weight | 185.63100 |
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| Density | 1.515 g/cm3 | Boiling Point | / |
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| Molecular Formula | C7H4ClNOS | Melting Point | 270-272ºC |
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| MSDS | / | Flash Point | / |
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Names
| Name | 6-chloro-1,2-benzothiazol-3-one |
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| Synonym | More Synonyms |
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Ticlatone BiologicalActivity
| Description | Ticlatone is an antifungal that can be used for the research of mycoses[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Fungal |
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| References | [1]. Lundell E, et, al. [Clinical studies on landromil (tiklaton) in treatment of mycoses]. Mykosen. 1971 Nov 1;14(11):531-3. |
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Chemical & Physical Properties
| Density | 1.515 g/cm3 |
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| Melting Point | 270-272ºC |
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| Molecular Formula | C7H4ClNOS |
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| Molecular Weight | 185.63100 |
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| Exact Mass | 184.97000 |
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| PSA | 61.10000 |
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| LogP | 2.24300 |
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| Index of Refraction | 1.669 |
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| InChIKey | POPOYOKQQAEISW-UHFFFAOYSA-N |
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| SMILES | O=c1[nH]sc2cc(Cl)ccc12 |
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| Storage condition | 2-8°C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DE4170000
- CHEMICAL NAME :
- 1,2-Benzisothiazolin-3-one, 6-chloro-
- CAS REGISTRY NUMBER :
- 70-10-0
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C7-H4-Cl-N-O-S
- MOLECULAR WEIGHT :
- 185.63
- WISWESSER LINE NOTATION :
- T56 BSMVJ FG
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >4300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 14,1306,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 14,1306,1964
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Safety Information
Customs
| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 6-chlorobenzisothiazolinone |
| 6-CHLORO-1,2-BENZISOTHIAZOL-3(2H)-ONE |
| Ticlatonum [INN-Latin] |
| 6-Chlor-3-oxo-2,3-dihydro-benzisothiazol |
| TICLATONE |
| 6-chloro-1,2-benzisothiazol-3-one |
| 6-chlorobenzo[d]isothiazol-3-one |
| Ticlatone [USAN:INN] |
| Landromil |
| Ticlatona [INN-Spanish] |
| 6-chloro-1,2-benzisothiazolin-3-one |
| Fer 1443 |
| 6-Chloro-1,2-benzisothiazolone |