Introduction：Basic information about CAS 59-58-5|Prosultiamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Prosultiamine |
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| CAS Number | 59-58-5 | Molecular Weight | 356.507 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 593.7±50.0 °C at 760 mmHg |
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| Molecular Formula | C15H24N4O2S2 | Melting Point | / |
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| MSDS | / | Flash Point | 312.9±30.1 °C |
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Names
| Name | Prosultiamine |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 593.7±50.0 °C at 760 mmHg |
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| Molecular Formula | C15H24N4O2S2 |
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| Molecular Weight | 356.507 |
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| Flash Point | 312.9±30.1 °C |
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| Exact Mass | 356.134064 |
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| PSA | 142.94000 |
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| LogP | 3.41 |
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| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
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| Index of Refraction | 1.620 |
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| InChIKey | UDCIYVVYDCXLSX-UHFFFAOYSA-N |
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| SMILES | CCCSSC(CCO)=C(C)N(C=O)Cc1cnc(C)nc1N |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- LQ0699000
- CHEMICAL NAME :
- Formamide, N-((4-amino-2-methyl-5-pyrimidinyl)methyl)-N-(4-hydro xy-1-methyl-2- (propyldithio)-1-butenyl)-
- CAS REGISTRY NUMBER :
- 59-58-5
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C15-H24-N4-O2-S2
- MOLECULAR WEIGHT :
- 356.55
- WISWESSER LINE NOTATION :
- T6N CNJ B1 DZ E1NVHY1&UY2QSS3
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,724,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 650 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,724,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 320 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,724,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 37500 mg/kg/15D-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- REFERENCE :
- INDRBA Indian Drugs. (Indian Drugs Manufacturers' Assoc., 102B, Poonam Chambers, Dr. A. B. Rd., Worli, Bombay 400 018, India) V.1- 1963- Volume(issue)/page/year: 12,13,1974/1975
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Safety Information
| Risk Phrases | R20/21/22 |
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| Safety Phrases | 26-36/37/39 |
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Synonyms
| Aneurimec |
| tiotiamina |
| Prosultiamine |
| 2-(2-Methyl-4-aminopyrimidin-5-yl)methylformamido-5-hydroxy-2-penten-3-yl Propyl Disulfide |
| Alinamine |
| TPD |
| Sintotiamina |
| neurvita |
| Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[(1E)-4-hydroxy-1-methyl-2-(propyldithio)-1-buten-1-yl]- |
| Proneurin |
| nervilon |
| N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-[(2E)-5-hydroxy-3-(propyldisulfanyl)-2-penten-2-yl]formamide |
| DTPT |
| EINECS 200-436-3 |
| nevriton |
| Nuvelbi V.C.A. |
| alinamin |
| N-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-N-[(2E)-5-hydroxy-3-(propyldisulfanyl)pent-2-en-2-yl]formamide |
| aliton |
| thiamine propyldisulfide |
| tipidi |
| nuvelbiv.c.a. |
| arinamine |
